Literature DB >> 19486296

Does the ribosome have initiation and elongation modes of translation?

Tanel Tenson1, Vasili Hauryliuk.   

Abstract

RNA polymerases differ functionally and structurally in the initiation phase of transcription, when polymerization of 8-12 nucleotides occurs, from the later phases of transcription. Here we argue that the ribosome also might have different properties when translating the first codons in open reading frames, as compared with the later phases of translation.

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Year:  2009        PMID: 19486296     DOI: 10.1111/j.1365-2958.2009.06741.x

Source DB:  PubMed          Journal:  Mol Microbiol        ISSN: 0950-382X            Impact factor:   3.501


  4 in total

1.  Allosteric vs. spontaneous exit-site (E-site) tRNA dissociation early in protein synthesis.

Authors:  Chunlai Chen; Benjamin Stevens; Jaskiran Kaur; Zeev Smilansky; Barry S Cooperman; Yale E Goldman
Journal:  Proc Natl Acad Sci U S A       Date:  2011-10-03       Impact factor: 11.205

2.  tRNA Fluctuations Observed on Stalled Ribosomes Are Suppressed during Ongoing Protein Synthesis.

Authors:  Ryan M Jamiolkowski; Chunlai Chen; Barry S Cooperman; Yale E Goldman
Journal:  Biophys J       Date:  2017-12-05       Impact factor: 4.033

3.  Extending the Spacing between the Shine-Dalgarno Sequence and P-Site Codon Reduces the Rate of mRNA Translocation.

Authors:  Hironao Wakabayashi; Chandani Warnasooriya; Dmitri N Ermolenko
Journal:  J Mol Biol       Date:  2020-06-13       Impact factor: 5.469

4.  Peptidyl transferase center decompaction and structural constraints during early protein elongation on the ribosome.

Authors:  Bin Jia; Tianlong Wang; Jean Lehmann
Journal:  Sci Rep       Date:  2021-12-15       Impact factor: 4.379

  4 in total

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