Literature DB >> 19485329

Scalarane-based sesterterpenoid RCE-protease inhibitors isolated from the Indonesian marine sponge Carteriospongia foliascens.

David E Williams1, Irwin Hollander, Larry Feldberg, Eileen Frommer, Robert Mallon, Akbar Tahir, Rob van Soest, Raymond J Andersen.   

Abstract

Two new 20,24-bishomo-25-norscalaranes, compounds 1 and 2, and two new and two known 20,24-bishomoscalaranes, compounds 3-6, have been isolated from the Indonesian marine sponge Carteriospongia foliascens. The structures of 1-6 were determined by spectroscopic analysis. Compounds 1 and 3-6 inhibit RCE-protease activity.

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Year:  2009        PMID: 19485329     DOI: 10.1021/np900042r

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  8 in total

Review 1.  Concepts and advances in cancer therapeutic vulnerabilities in RAS membrane targeting.

Authors:  James V Michael; Lawrence E Goldfinger
Journal:  Semin Cancer Biol       Date:  2017-12-02       Impact factor: 15.707

2.  Modulation of the inhibitor properties of dipeptidyl (acyloxy)methyl ketones toward the CaaX proteases.

Authors:  Anne-Marie R Dechert; James P MacNamara; Sarah R Breevoort; Emily R Hildebrandt; Ned W Hembree; Adam C Rea; Duncan E McLain; Stephen B Porter; Walter K Schmidt; Timothy M Dore
Journal:  Bioorg Med Chem       Date:  2010-07-21       Impact factor: 3.641

Review 3.  Marine pharmacology in 2009-2011: marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis, and antiviral activities; affecting the immune and nervous systems, and other miscellaneous mechanisms of action.

Authors:  Alejandro M S Mayer; Abimael D Rodríguez; Orazio Taglialatela-Scafati; Nobuhiro Fusetani
Journal:  Mar Drugs       Date:  2013-07-16       Impact factor: 5.118

Review 4.  Secondary Metabolites from the Marine Sponge Genus Phyllospongia.

Authors:  Huawei Zhang; Menglian Dong; Hong Wang; Phillip Crews
Journal:  Mar Drugs       Date:  2017-01-06       Impact factor: 5.118

5.  Antileukemic Scalarane Sesterterpenoids and Meroditerpenoid from Carteriospongia (Phyllospongia) sp., Induce Apoptosis via Dual Inhibitory Effects on Topoisomerase II and Hsp90.

Authors:  Kuei-Hung Lai; Yi-Chang Liu; Jui-Hsin Su; Mohamed El-Shazly; Chih-Fung Wu; Ying-Chi Du; Yu-Ming Hsu; Juan-Cheng Yang; Ming-Kai Weng; Chia-Hua Chou; Guan-Yu Chen; Yu-Cheng Chen; Mei-Chin Lu
Journal:  Sci Rep       Date:  2016-10-31       Impact factor: 4.379

Review 6.  Rce1: mechanism and inhibition.

Authors:  Shahienaz E Hampton; Timothy M Dore; Walter K Schmidt
Journal:  Crit Rev Biochem Mol Biol       Date:  2018-02-09       Impact factor: 8.250

7.  Isolation of Scalarane-Type Sesterterpenoids from the Marine Sponge Dysidea sp. and Stereochemical Reassignment of 12-epi-Phyllactone D/E.

Authors:  A-Young Shin; Arang Son; Changhoon Choi; Jihoon Lee
Journal:  Mar Drugs       Date:  2021-11-09       Impact factor: 5.118

Review 8.  Chemical Diversity and Biological Activity of Secondary Metabolites Isolated from Indonesian Marine Invertebrates.

Authors:  Fauzia Izzati; Mega Ferdina Warsito; Asep Bayu; Anggia Prasetyoputri; Akhirta Atikana; Linda Sukmarini; Siti Irma Rahmawati; Masteria Yunovilsa Putra
Journal:  Molecules       Date:  2021-03-27       Impact factor: 4.411

  8 in total

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