Literature DB >> 19484314

Is there any role of resecting the stomach to ameliorate weight loss and sugar control in morbidly obese diabetic patients?

Eldo E Frezza1, Susan E Wozniak, Laura Gee, Mitchell Wacthel.   

Abstract

BACKGROUND: Among the restrictive procedures the role of restrictive vs. resecting the stomach is still ambiguous. This study evaluate which is the role of the stomach with respect to blood glucose levels (BG) and percent excess weight loss (EWL) over the 18 months after restrictive procedures in morbid obese diabetic patients.
METHODS: We retrospectively compared a group of patients who underwent partial gastrectomy (just part of the gastric body) with gastric banding (GBSR; n=27), sleeve gastrectomy (part of gastric body and complete fundus resection; LSG; n=53) to laparoscopic gastric banding (LAGB; n=100). Differences among groups at 3, 6, 12, and 18 months were evaluated by analysis of variance. The three cohorts were diabetic patients similar in BMI, age, and gender.
RESULTS: At 12 and 18 months, LSG had higher EWL (P<0.05) and lower BG (P<0.05) than did either LAGB or GBSR. There were no operative deaths. COMPLICATIONS: LAGB-two staple-line oozing, two wound infections; LSG-one hemorrhage, two staple-line oozing, two leaks; GBSR-one hemorrhage, two wound infections. All complications were readily treated.
CONCLUSIONS: LSG provides better weight loss and glucose control at 1 year and 1.5 years after surgery than does either LAGB or GBSR, suggesting that gastric fundus resection plays an important, not yet well-defined, role.

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Year:  2009        PMID: 19484314     DOI: 10.1007/s11695-009-9868-9

Source DB:  PubMed          Journal:  Obes Surg        ISSN: 0960-8923            Impact factor:   4.129


  38 in total

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2.  The decrease in plasma ghrelin concentrations following bariatric surgery depends on the functional integrity of the fundus.

Authors:  Gema Frühbeck; Alberto Diez-Caballero; M Jesús Gil; Inés Montero; Javier Gómez-Ambrosi; Javier Salvador; Javier A Cienfuegos
Journal:  Obes Surg       Date:  2004-05       Impact factor: 4.129

Review 3.  Laparoscopic adjustable gastric band.

Authors:  George A Fielding; Christine J Ren
Journal:  Surg Clin North Am       Date:  2005-02       Impact factor: 2.741

Review 4.  Ghrelin, the peripheral hunger hormone.

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5.  Effectiveness of laparoscopic sleeve gastrectomy (first stage of biliopancreatic diversion with duodenal switch) on co-morbidities in super-obese high-risk patients.

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6.  Biliopancreatic Diversion with a New Type of Gastrectomy.

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7.  Gastric pacing as therapy for morbid obesity: preliminary results.

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8.  Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans.

Authors:  H Ariyasu; K Takaya; T Tagami; Y Ogawa; K Hosoda; T Akamizu; M Suda; T Koh; K Natsui; S Toyooka; G Shirakami; T Usui; A Shimatsu; K Doi; H Hosoda; M Kojima; K Kangawa; K Nakao
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9.  Comparison of rates of resolution of diabetes mellitus after gastric banding, gastric bypass, and biliopancreatic diversion.

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10.  Combined laparoscopic gastric banding and stomach reduction (GBSR): initial experience after 1 year.

Authors:  Eldo E Frezza; Haleigh Herbert; Mitchell S Wachtel
Journal:  Obes Surg       Date:  2008-04-08       Impact factor: 4.129

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2.  Sleeve gastrectomy improves glucose homeostasis in Zucker diabetic fatty rats.

Authors:  Jean Christophe Lifante; Luca Milone; Judith Korner; Gift Kopsombut; Manu Sebastian; William B Inabnet
Journal:  Obes Surg       Date:  2012-07       Impact factor: 4.129

3.  Improvement in insulin sensitivity and β-cell function following ileal interposition with sleeve gastrectomy in type 2 diabetic patients: potential mechanisms.

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Review 4.  Excessive weight loss after sleeve gastrectomy: a systematic review.

Authors:  Lars Fischer; Caroline Hildebrandt; Thomas Bruckner; Hannes Kenngott; Georg R Linke; Tobias Gehrig; Markus W Büchler; Beat P Müller-Stich
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5.  Impact of laparoscopic sleeve gastrectomy and laparoscopic gastric bypass on HbA1c blood level and pharmacological treatment of type 2 diabetes mellitus in severe or morbidly obese patients. Results of a multicenter prospective study at 1 year.

Authors:  David Nocca; Fabre Guillaume; Patrick Noel; Marie Christine Picot; Rajesh Aggarwal; Moez El Kamel; Roxanne Schaub; Charles de Seguin de Hons; Eric Renard; Jean Michel Fabre
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6.  Impact of laparoscopic sleeve gastrectomy on body mass index, ghrelin, insulin and lipid levels in 100 obese patients.

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