Literature DB >> 19483748

Twist: a new link from hypoxia to fibrosis.

Wibke Bechtel1, Michael Zeisberg2.   

Abstract

Sun et al. demonstrate that hypoxia causes epithelial-to-mesenchymal transition by activating Twist, a transcription factor known to mediate both acquisition of a mesenchymal phenotype and resistance to apoptosis in cancer cells. This study provides clues as to how hypoxia and transforming growth factor-beta can collaborate to drive renal fibrogenesis.

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Year:  2009        PMID： 19483748     DOI： 10.1038/ki.2009.102

Source DB:  PubMed          Journal:  Kidney Int        ISSN： 0085-2538            Impact factor:   10.612


  9 in total

Review 1.  The role of cancer-associated myofibroblasts in intrahepatic cholangiocarcinoma.

Authors:  Alphonse E Sirica
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2011-11-29       Impact factor: 46.802

2.  The effect of the partial obstruction site of the renal vein on testis and kidney in rats: is the traditional animal model suitable for varicocele research?

Authors:  Ki Won Ko; Ji Yun Chae; Soo Woong Kim; Du Geon Moon; Je Jong Kim; Duck Ki Yoon; Jae Young Park
Journal:  Korean J Urol       Date:  2010-08-18

3.  SNAIL gene inhibited by hypoxia-inducible factor 1α (HIF-1α) in epithelial ovarian cancer.

Authors:  Pengnan Zhang; Yanmei Liu; Youji Feng; Shujun Gao
Journal:  Int J Immunopathol Pharmacol       Date:  2016-04-04       Impact factor: 3.219

4.  Constitutive proteasomal degradation of TWIST-1 in epithelial-ovarian cancer stem cells impacts differentiation and metastatic potential.

Authors:  G Yin; A B Alvero; V Craveiro; J C Holmberg; H-H Fu; M K Montagna; Y Yang; I Chefetz-Menaker; S Nuti; M Rossi; D-A Silasi; T Rutherford; G Mor
Journal:  Oncogene       Date:  2012-02-20       Impact factor: 9.867

Review 5.  Signalling pathways involved in hypoxia-induced renal fibrosis.

Authors:  Minna Liu; Xiaoxuan Ning; Rong Li; Zhen Yang; Xiaoxia Yang; Shiren Sun; Qi Qian
Journal:  J Cell Mol Med       Date:  2017-01-18       Impact factor: 5.310

Review 6.  Emerging role of Twist1 in fibrotic diseases.

Authors:  Xiaoxuan Ning; Kun Zhang; Qingfeng Wu; Minna Liu; Shiren Sun
Journal:  J Cell Mol Med       Date:  2018-01-05       Impact factor: 5.310

Review 7.  Emerging Therapeutic Strategies for Attenuating Tubular EMT and Kidney Fibrosis by Targeting Wnt/β-Catenin Signaling.

Authors:  Lichao Hu; Mengyuan Ding; Weichun He
Journal:  Front Pharmacol       Date:  2022-01-10       Impact factor: 5.810

8.  Tubular Overexpression of Angiopoietin-1 Attenuates Renal Fibrosis.

Authors:  Sudhir Singh; Scott R Manson; Heedoo Lee; Yeawon Kim; Tuoen Liu; Qiusha Guo; Julio J Geminiani; Paul F Austin; Ying Maggie Chen
Journal:  PLoS One       Date:  2016-07-25       Impact factor: 3.240

9.  Regulatory Roles of Dclk1 in Epithelial Mesenchymal Transition and Cancer Stem Cells.

Authors:  P Chandrakesan; J Panneerselvam; D Qu; N Weygant; R May; M S Bronze; C W Houchen
Journal:  J Carcinog Mutagen       Date:  2016-03-07
  9 in total

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