| Literature DB >> 19483741 |
Hatem A Azim1, Fedro A Peccatori, Sarah J Liptrott, Chiara Catania, Aron Goldhirsch.
Abstract
BACKGROUND: A 29-year-old woman was diagnosed with lymph-node-positive, steroid-hormone-receptor-negative and HER2/neu-positive breast cancer. She underwent surgery followed by cyclophosphamide, epirubicin, and 5-fluorouracil chemotherapy, and received radiotherapy followed by trastuzumab therapy for 1 year. During the tenth month of trastuzumab therapy, the patient reported a missed period and had a positive pregnancy test. INVESTIGATIONS: Physical examination, pregnancy test, echocardiography. DIAGNOSIS: Unintended pregnancy during adjuvant trastuzumab therapy. MANAGEMENT: Cessation of trastuzumab and close monitoring of mother and fetus during pregnancy.Entities:
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Year: 2009 PMID： 19483741 DOI： 10.1038/nrclinonc.2009.48
Source DB: PubMed Journal: Nat Rev Clin Oncol ISSN： 1759-4774 Impact factor: 66.675