Leonid Kalichman1, Gabriela Hernández-Molina. 1. Department of Physical Therapy, Recanati School for Community Health Professions, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel. kleonid@bgu.ac.il
Abstract
OBJECTIVES: Hand osteoarthritis (OA) is a highly prevalent condition with a wide spectrum of clinical presentations. We review herein the prevalence, impact on hand function, and various risk factors related to hand OA. METHODS: PubMed and MEDLINE databases (1950-2009) were searched for the keywords: "hand," "hand osteoarthritis," "distal interphalangeal," "proximal interphalangeal," "metacarpophalangeal," and "carpometacarpal." Published material emphasizing cohort, cross-sectional, and case-control studies regarding epidemiology, clinical features, functional impairment, and associated risk factors of hand OA were included. RESULTS: Hand OA is a heterogeneous, age- and gender-dependent disorder, occurring more frequently in women over 50 years of age. In the elderly population, the prevalence of radiographic hand OA can reach 80%. OA has a strong genetic predisposition, apparently gender- and phenotype-specific. A history of heavy manual labor or a repetitive use of the hand also has been linked to OA. Other variables such as weight, smoking, joint hyperlaxity, age of menarche, bone and cartilage mineralization factors, grip strength, and handedness may play a role. Symptomatic hand OA may cause functional impairment due to loss of strength, thus limiting the individual's ability to perform daily tasks. CONCLUSIONS: Several risk factors for hand OA have been identified; however, their interrelationship is not clearly understood. The development of preventive strategies and future research goals is needed. Copyright 2010 Elsevier Inc. All rights reserved.
OBJECTIVES:Hand osteoarthritis (OA) is a highly prevalent condition with a wide spectrum of clinical presentations. We review herein the prevalence, impact on hand function, and various risk factors related to hand OA. METHODS: PubMed and MEDLINE databases (1950-2009) were searched for the keywords: "hand," "hand osteoarthritis," "distal interphalangeal," "proximal interphalangeal," "metacarpophalangeal," and "carpometacarpal." Published material emphasizing cohort, cross-sectional, and case-control studies regarding epidemiology, clinical features, functional impairment, and associated risk factors of hand OA were included. RESULTS: Hand OA is a heterogeneous, age- and gender-dependent disorder, occurring more frequently in women over 50 years of age. In the elderly population, the prevalence of radiographic hand OA can reach 80%. OA has a strong genetic predisposition, apparently gender- and phenotype-specific. A history of heavy manual labor or a repetitive use of the hand also has been linked to OA. Other variables such as weight, smoking, joint hyperlaxity, age of menarche, bone and cartilage mineralization factors, grip strength, and handedness may play a role. Symptomatic hand OA may cause functional impairment due to loss of strength, thus limiting the individual's ability to perform daily tasks. CONCLUSIONS: Several risk factors for hand OA have been identified; however, their interrelationship is not clearly understood. The development of preventive strategies and future research goals is needed. Copyright 2010 Elsevier Inc. All rights reserved.
Authors: D S Amaral; A L B P Duarte; S S Barros; S V Cavalcanti; A Ranzolin; V M M Leite; A T Dantas; A S C R C Oliveira; P S Santos; J C A Silva; C D L Marques Journal: Rheumatol Int Date: 2017-11-28 Impact factor: 2.631
Authors: B A Lakin; D J Ellis; J S Shelofsky; J D Freedman; M W Grinstaff; B D Snyder Journal: Osteoarthritis Cartilage Date: 2015-06-09 Impact factor: 6.576
Authors: Kasper Huétink; Berend C Stoel; Iain Watt; Margreet Kloppenburg; Johan L Bloem; Steve H Malm; Ronald Van't Klooster; Rob G H H Nelissen Journal: Clin Rheumatol Date: 2014-09-13 Impact factor: 2.980
Authors: N X Jain; A E Barr-Gillespie; B D Clark; D M Kietrys; C K Wade; J Litvin; S N Popoff; M F Barbe Journal: J Musculoskelet Neuronal Interact Date: 2014-03 Impact factor: 2.041