Literature DB >> 19481976

The scent of Mycobacterium tuberculosis--part II breath.

Mona Syhre1, Laurens Manning, Suparat Phuanukoonnon, Paul Harino, Stephen T Chambers.   

Abstract

Recent figures show that tuberculosis (TB) is advancing and killing more than two million people annually, yet no breakthrough in rapid diagnostics is in sight. Volatile metabolites of Mycobacterium tuberculosis (MTB) may provide just that. It is well established that MTB produces nicotinic acid in vitro. We have converted the free acid into methyl nicotinate and detected statistically significant differences in the breath of smear positive patients compared with healthy (smear negative) subjects.

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Year:  2009        PMID： 19481976     DOI： 10.1016/j.tube.2009.04.003

Source DB:  PubMed          Journal:  Tuberculosis (Edinb)        ISSN： 1472-9792            Impact factor:   3.131


  42 in total

1.  Electronic-nose technology using sputum samples in diagnosis of patients with tuberculosis.

Authors:  Arend Kolk; Michael Hoelscher; Leonard Maboko; Jutta Jung; Sjoukje Kuijper; Michael Cauchi; Conrad Bessant; Stella van Beers; Ritaban Dutta; Tim Gibson; Klaus Reither
Journal:  J Clin Microbiol       Date:  2010-08-18       Impact factor: 5.948

2.  Breathing new life into pneumonia diagnostics.

Authors:  David R Murdoch; Katherine L O'Brien; J Anthony G Scott; Ruth A Karron; Niranjan Bhat; Amanda J Driscoll; Maria Deloria Knoll; Orin S Levine
Journal:  J Clin Microbiol       Date:  2009-09-09       Impact factor: 5.948

Review 3.  Towards a point-of-care test for active tuberculosis: obstacles and opportunities.

Authors:  Ruth McNerney; Peter Daley
Journal:  Nat Rev Microbiol       Date:  2011-03       Impact factor: 60.633

4.  Comprehensive volatile metabolic fingerprinting of bacterial and fungal pathogen groups.

Authors:  Christiaan A Rees; Alison Burklund; Pierre-Hugues Stefanuto; Joseph D Schwartzman; Jane E Hill
Journal:  J Breath Res       Date:  2018-01-03       Impact factor: 3.262

5.  Mycobacterial nicotinate mononucleotide adenylyltransferase: structure, mechanism, and implications for drug discovery.

Authors:  Irina A Rodionova; Harmon J Zuccola; Leonardo Sorci; Alexander E Aleshin; Marat D Kazanov; Chen-Ting Ma; Eduard Sergienko; Eric J Rubin; Christopher P Locher; Andrei L Osterman
Journal:  J Biol Chem       Date:  2015-01-28       Impact factor: 5.157

6.  Brain Injury Alters Volatile Metabolome.

Authors:  Bruce A Kimball; Akiva S Cohen; Amy R Gordon; Maryanne Opiekun; Talia Martin; Jaclynn Elkind; Johan N Lundström; Gary K Beauchamp
Journal:  Chem Senses       Date:  2016-02-28       Impact factor: 3.160

Review 7.  Breathomics for the clinician: the use of volatile organic compounds in respiratory diseases.

Authors:  Wadah Ibrahim; Liesl Carr; Rebecca Cordell; Michael J Wilde; Dahlia Salman; Paul S Monks; Paul Thomas; Chris E Brightling; Salman Siddiqui; Neil J Greening
Journal:  Thorax       Date:  2021-01-07       Impact factor: 9.139

8.  Diagnosis of tuberculosis by trained African giant pouched rats and confounding impact of pathogens and microflora of the respiratory tract.

Authors:  Georgies F Mgode; Bart J Weetjens; Thorben Nawrath; Christophe Cox; Maureen Jubitana; Robert S Machang'u; Stéphan Cohen-Bacrie; Marielle Bedotto; Michel Drancourt; Stefan Schulz; Stefan H E Kaufmann
Journal:  J Clin Microbiol       Date:  2011-11-30       Impact factor: 5.948

Review 9.  Bacterial volatiles and diagnosis of respiratory infections.

Authors:  James E Graham
Journal:  Adv Appl Microbiol       Date:  2013       Impact factor: 5.086

10.  Robust detection of P. aeruginosa and S. aureus acute lung infections by secondary electrospray ionization-mass spectrometry (SESI-MS) breathprinting: from initial infection to clearance.

Authors:  Jiangjiang Zhu; Jaime Jiménez-Díaz; Heather D Bean; Nirav A Daphtary; Minara I Aliyeva; Lennart K A Lundblad; Jane E Hill
Journal:  J Breath Res       Date:  2013-07-18       Impact factor: 3.262
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