Literature DB >> 19481867

Heterotopic ossification in burns: our experience and literature reviews.

Hung-Chang Chen1, Jui-Yung Yang, Shiow-Shuh Chuang, Chun-Yuan Huang, Shih-Yi Yang.   

Abstract

PURPOSES: Heterotopic ossification (HO) is an uncommon, but high profile complication of burns. In this paper, a retrospective study was undertaken to evaluate our treatment and results of HO. Relevant literature was also reviewed to search for new advances in prevention and management for patients with HO after burns.
MATERIALS AND METHODS: A retrospective study was undertaken in Chang Gung Memorial Hospital, Linkou. We collected 12 patients who suffered from HO after burn and received operation in our hospital between June 2000 and September 2007. The data was expressed as mean.
RESULTS: Patients' gender distribution was 10 males and 2 females. The mean age was 43 years old (range, 30-59). Causes of burn were flame burn (75%), scald burn (8%), contact burn (8%), and high-voltage electrical burn (8%). Mean TBSA was 39% (range, 8-90%). Nine of 12 patients (75%) were admitted to intensive care unit (ICU) and 6 (50%) received mechanical ventilator support. The mean ICU stay was 82 days (range, 26-240 days). The elbow was the most commonly affected joint (92%). The outcome of surgery was acceptable in all elbows at the time of surgery. The mean ROMs before surgery were 31 degrees (range, 0-75 degrees). The mean ROMs after surgery were 99 degrees (range, 70-115 degrees); mean gain was 68 degrees (range, 35-115 degrees). One (8%) patients had recurrent HO after operation. The mean outpatient department follow-up time was 14.6 months (range, 1-40 months). The incidence of HO in our burn center is 0.15%.
CONCLUSION: Although HO after burn is uncommon, physicians should keep the complication in mind. When burn patients complain decreased ROM or "locking sign" in their joints, X-ray examination is indicated to rule out HO. Surgery is the treatment of choice when the diagnosis of HO is confirmed.

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Year:  2009        PMID: 19481867     DOI: 10.1016/j.burns.2008.03.002

Source DB:  PubMed          Journal:  Burns        ISSN: 0305-4179            Impact factor:   2.744


  27 in total

1.  Vascular patterning in human heterotopic ossification.

Authors:  Margaret Cocks; Aditya Mohan; Carolyn A Meyers; Catherine Ding; Benjamin Levi; Edward McCarthy; Aaron W James
Journal:  Hum Pathol       Date:  2017-03-14       Impact factor: 3.466

2.  Heterotopic ossification of the elbows in a major petrol burn.

Authors:  Shahriar Raj Zaman
Journal:  BMJ Case Rep       Date:  2012-08-27

3.  Hip fracture risk in patients with burn injury: a retrospective cohort study in Taiwan.

Authors:  O Kaewboonchoo; F C Sung; C L Lin; H C Hsu; C T Kuo
Journal:  Osteoporos Int       Date:  2017-09-05       Impact factor: 4.507

4.  Management of pelvic heterotopic ossification post-myocutaneous flap reconstruction of a sacral pressure ulcer.

Authors:  Colin W McInnes; Richard Ak Reynolds; Jugpal S Arneja
Journal:  Can J Plast Surg       Date:  2011

5.  Investigation into Possible Association of Oxandrolone and Heterotopic Ossification Following Burn Injury.

Authors:  Catherine R Thorpe; Serra Ucer Ozgurel; Laura C Simko; Richard Goldstein; Gabrielle G Grant; Chase Pagani; Charles Hwang; Kaetlin Vasquez; Michael Sorkin; Anita Vaishampayan; Jeremy Goverman; Robert L Sheridan; Jonathan Friedstat; John T Schulz; Jeffrey C Schneider; Benjamin Levi; Colleen M Ryan
Journal:  J Burn Care Res       Date:  2019-06-21       Impact factor: 1.845

6.  Risk factors for the development of heterotopic ossification in seriously burned adults: A National Institute on Disability, Independent Living and Rehabilitation Research burn model system database analysis.

Authors:  Benjamin Levi; Prakash Jayakumar; Avi Giladi; Jesse B Jupiter; David C Ring; Karen Kowalske; Nicole S Gibran; David Herndon; Jeffrey C Schneider; Colleen M Ryan
Journal:  J Trauma Acute Care Surg       Date:  2015-11       Impact factor: 3.313

7.  Burn injury enhances bone formation in heterotopic ossification model.

Authors:  Jonathan R Peterson; Sara De La Rosa; Hongli Sun; Oluwatobi Eboda; Katherine E Cilwa; Alexis Donneys; Michael Morris; Steven R Buchman; Paul S Cederna; Paul H Krebsbach; Stewart C Wang; Benjamin Levi
Journal:  Ann Surg       Date:  2014-05       Impact factor: 12.969

Review 8.  Biology and principles of scar management and burn reconstruction.

Authors:  Edward E Tredget; Benjamin Levi; Matthias B Donelan
Journal:  Surg Clin North Am       Date:  2014-08       Impact factor: 2.741

9.  Risk factors for the development of heterotopic ossification after knee dislocation.

Authors:  Daniel B Whelan; Andrew P Dold; Tomce Trajkovski; Jas Chahal
Journal:  Clin Orthop Relat Res       Date:  2014-09       Impact factor: 4.176

Review 10.  Reconciling the effects of inflammatory cytokines on mesenchymal cell osteogenic differentiation.

Authors:  Sagar Deshpande; Aaron W James; Jordan Blough; Alexis Donneys; Stewart C Wang; Paul S Cederna; Steven R Buchman; Benjamin Levi
Journal:  J Surg Res       Date:  2013-08-06       Impact factor: 2.192

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