Literature DB >> 19481520

The CUL4 enigma: culling DNA repair factors.

Kaoru Sugasawa1.   

Abstract

Although CUL4-containing ubiquitin ligases regulate DNA repair and DNA damage checkpoints, Liu et al. (2009) report in this issue of Molecular Cell that Cul4a-deficient mice exhibit surprising resistance to ultraviolet-induced skin tumors, providing insight into how ubiquitination regulates genome integrity.

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Year:  2009        PMID： 19481520     DOI： 10.1016/j.molcel.2009.05.009

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  14 in total

1.  Clinical significance of CUL4A in human prostate cancer.

Authors:  Gang Liu; Zengjun Zhu; Fang Lang; Bao Li; Dianjun Gao
Journal:  Tumour Biol       Date:  2015-06-03

2.  Epidermal growth factor receptor protects proliferating cell nuclear antigen from cullin 4A protein-mediated proteolysis.

Authors:  Yuan-Hung Lo; Po-Chun Ho; Shao-Chun Wang
Journal:  J Biol Chem       Date:  2012-06-12       Impact factor: 5.157

Review 3.  Expanding molecular roles of UV-DDB: Shining light on genome stability and cancer.

Authors:  Maria Beecher; Namrata Kumar; Sunbok Jang; Vesna Rapić-Otrin; Bennett Van Houten
Journal:  DNA Repair (Amst)       Date:  2020-04-27

4.  Cell Autonomous and Nonautonomous Function of CUL4B in Mouse Spermatogenesis.

Authors:  Yan Yin; Liren Liu; Chenyi Yang; Congxing Lin; George Michael Veith; Caihong Wang; Peter Sutovsky; Pengbo Zhou; Liang Ma
Journal:  J Biol Chem       Date:  2016-02-04       Impact factor: 5.157

5.  DDB1- and CUL4-associated factor 8 plays a critical role in spermatogenesis.

Authors:  Xiuli Zhang; Zhizhou Xia; Xingyu Lv; Donghe Li; Mingzhu Liu; Ruihong Zhang; Tong Ji; Ping Liu; Ruibao Ren
Journal:  Front Med       Date:  2021-04-14       Impact factor: 4.592

6.  CUL4A overexpression enhances lung tumor growth and sensitizes lung cancer cells to erlotinib via transcriptional regulation of EGFR.

Authors:  Yunshan Wang; Pengju Zhang; Ziming Liu; Qin Wang; Mingxin Wen; Yuli Wang; Hongtu Yuan; Jian-Hua Mao; Guangwei Wei
Journal:  Mol Cancer       Date:  2014-11-21       Impact factor: 27.401

7.  Autophagic UVRAG Promotes UV-Induced Photolesion Repair by Activation of the CRL4(DDB2) E3 Ligase.

Authors:  Yongfei Yang; Shanshan He; Qiaoxiu Wang; Fan Li; Mi-Jeong Kwak; Sally Chen; Douglas O'Connell; Tian Zhang; Sara Dolatshahi Pirooz; Yong Heui Jeon; Nyam-Osor Chimge; Baruch Frenkel; Younho Choi; Grace M Aldrovandi; Byung-Ha Oh; Zengqiang Yuan; Chengyu Liang
Journal:  Mol Cell       Date:  2016-05-19       Impact factor: 17.970

Review 8.  Targeting NEDDylation as a Novel Approach to Improve the Treatment of Head and Neck Cancer.

Authors:  Trace M Jones; Jennifer S Carew; Julie E Bauman; Steffan T Nawrocki
Journal:  Cancers (Basel)       Date:  2021-06-29       Impact factor: 6.575

9.  Chromatin retention of DNA damage sensors DDB2 and XPC through loss of p97 segregase causes genotoxicity.

Authors:  Marjo-Riitta Puumalainen; Davor Lessel; Peter Rüthemann; Nina Kaczmarek; Karin Bachmann; Kristijan Ramadan; Hanspeter Naegeli
Journal:  Nat Commun       Date:  2014-04-28       Impact factor: 14.919

10.  CUL4A contributes to the biology of basal-like breast tumors through modulation of cell growth and antitumor immune response.

Authors:  Laura P Saucedo-Cuevas; Isabel Ruppen; Pilar Ximénez-Embún; Samuel Domingo; Javier Gayarre; Javier Muñoz; Jose M Silva; María J García; Javier Benítez
Journal:  Oncotarget       Date:  2014-04-30
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