Literature DB >> 19481516

Breaching the boundaries that safeguard against repression.

Vijay K Tiwari1, Stephen B Baylin.   

Abstract

In a recent issue of Molecular Cell, Witcher and Emerson (2009) demonstrate that CTCF loss of function, via defective steps in poly (ADP-ribosyl)ation, may predispose key genes in cancer cells to addition of abnormal promoter DNA methylation and silencing.

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Year:  2009        PMID： 19481516      PMCID： PMC3577062          DOI： 10.1016/j.molcel.2009.05.007

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  11 in total

1.  High-resolution profiling of histone methylations in the human genome.

Authors:  Artem Barski; Suresh Cuddapah; Kairong Cui; Tae-Young Roh; Dustin E Schones; Zhibin Wang; Gang Wei; Iouri Chepelev; Keji Zhao
Journal:  Cell       Date:  2007-05-18       Impact factor: 41.582

2.  CTCF and its protein partners: divide and rule?

Authors:  Jordanka Zlatanova; Paola Caiafa
Journal:  J Cell Sci       Date:  2009-05-01       Impact factor: 5.285

Review 3.  The epigenomics of cancer.

Authors:  Peter A Jones; Stephen B Baylin
Journal:  Cell       Date:  2007-02-23       Impact factor: 41.582

4.  Role of nucleosomal occupancy in the epigenetic silencing of the MLH1 CpG island.

Authors:  Joy C Lin; Shinwu Jeong; Gangning Liang; Daiya Takai; Merhnaz Fatemi; Yvonne C Tsai; Gerda Egger; Einav Nili Gal-Yam; Peter A Jones
Journal:  Cancer Cell       Date:  2007-11       Impact factor: 31.743

5.  Epigenetic silencing of the p16(INK4a) tumor suppressor is associated with loss of CTCF binding and a chromatin boundary.

Authors:  Michael Witcher; Beverly M Emerson
Journal:  Mol Cell       Date:  2009-05-15       Impact factor: 17.970

Review 6.  Epigenetics in human disease and prospects for epigenetic therapy.

Authors:  Gerda Egger; Gangning Liang; Ana Aparicio; Peter A Jones
Journal:  Nature       Date:  2004-05-27       Impact factor: 49.962

7.  PcG proteins, DNA methylation, and gene repression by chromatin looping.

Authors:  Vijay K Tiwari; Kelly M McGarvey; Julien D F Licchesi; Joyce E Ohm; James G Herman; Dirk Schübeler; Stephen B Baylin
Journal:  PLoS Biol       Date:  2008-12-02       Impact factor: 8.029

8.  Variant histone H2A.Z is globally localized to the promoters of inactive yeast genes and regulates nucleosome positioning.

Authors:  Benoît Guillemette; Alain R Bataille; Nicolas Gévry; Maryse Adam; Mathieu Blanchette; François Robert; Luc Gaudreau
Journal:  PLoS Biol       Date:  2005-11-01       Impact factor: 8.029

9.  CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery.

Authors:  Tiziana Guastafierro; Barbara Cecchinelli; Michele Zampieri; Anna Reale; Giuseppe Riggio; Olga Sthandier; Gabriella Zupi; Lilia Calabrese; Paola Caiafa
Journal:  J Biol Chem       Date:  2008-06-05       Impact factor: 5.157

10.  Histone H2A.Z and DNA methylation are mutually antagonistic chromatin marks.

Authors:  Daniel Zilberman; Devin Coleman-Derr; Tracy Ballinger; Steven Henikoff
Journal:  Nature       Date:  2008-09-24       Impact factor: 49.962
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  4 in total

Review 1.  Harnessing the potential of epigenetic therapy to target solid tumors.

Authors:  Nita Ahuja; Hariharan Easwaran; Stephen B Baylin
Journal:  J Clin Invest       Date:  2014-01-02       Impact factor: 14.808

2.  Tumour-specific methylation of PTPRG intron 1 locus in sporadic and Lynch syndrome colorectal cancer.

Authors:  Eddy H J van Roon; Noël F C C de Miranda; Merlijn P van Nieuwenhuizen; Emile J de Meijer; Marjo van Puijenbroek; Pearlly S Yan; Tim H-M Huang; Tom van Wezel; Hans Morreau; Judith M Boer
Journal:  Eur J Hum Genet       Date:  2010-12-08       Impact factor: 4.246

3.  ADP-ribose polymers localized on Ctcf-Parp1-Dnmt1 complex prevent methylation of Ctcf target sites.

Authors:  Michele Zampieri; Tiziana Guastafierro; Roberta Calabrese; Fabio Ciccarone; Maria G Bacalini; Anna Reale; Mariagrazia Perilli; Claudio Passananti; Paola Caiafa
Journal:  Biochem J       Date:  2012-01-15       Impact factor: 3.857

4.  Poly(ADP-ribosyl)ation is involved in the epigenetic control of TET1 gene transcription.

Authors:  Fabio Ciccarone; Elisabetta Valentini; Maria Giulia Bacalini; Michele Zampieri; Roberta Calabrese; Tiziana Guastafierro; Germano Mariano; Anna Reale; Claudio Franceschi; Paola Caiafa
Journal:  Oncotarget       Date:  2014-11-15
  4 in total

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