Literature DB >> 19481447

Antimitotic activity of lobaric acid and a new benzofuran, sakisacaulon A from Stereocaulon sasakii.

Hiroshi Morita1, Tomoe Tsuchiya, Koji Kishibe, Sayaka Noya, Motoo Shiro, Yusuke Hirasawa.   

Abstract

Lobaric acid (1) has been isolated from lichen, Stereocaulon sasakii together with a new benzofuran, sakisacaulon A (2). Lobaric acid (1) inhibited the polymerization of tubulin. Structure-activity relationship of lobaric acid and its derivatives on inhibitory activity of tubulin polymerization was discussed.

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Year:  2009        PMID: 19481447     DOI: 10.1016/j.bmcl.2009.03.170

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  5 in total

1.  Identification of small molecule inhibitors of the Chikungunya virus nsP1 RNA capping enzyme.

Authors:  Kristen M Feibelman; Benjamin P Fuller; Linfeng Li; Daniel V LaBarbera; Brian J Geiss
Journal:  Antiviral Res       Date:  2018-04-20       Impact factor: 5.970

2.  Skin Barrier Recovery by Protease-Activated Receptor-2 Antagonist Lobaric Acid.

Authors:  Yeon Ah Joo; Hyunjin Chung; Sohyun Yoon; Jong Il Park; Ji Eun Lee; Cheol Hwan Myung; Jae Sung Hwang
Journal:  Biomol Ther (Seoul)       Date:  2016-09-01       Impact factor: 4.634

3.  Lobaric Acid Inhibits VCAM-1 Expression in TNF-α-Stimulated Vascular Smooth Muscle Cells via Modulation of NF-κB and MAPK Signaling Pathways.

Authors:  Ii-Seul Kwon; Joung-Han Yim; Hong-Kum Lee; Suhkneung Pyo
Journal:  Biomol Ther (Seoul)       Date:  2016-01-01       Impact factor: 4.634

4.  Bioactive Terphenyls Isolated from the Antarctic Lichen Stereocaulon alpinum.

Authors:  Kim-Hoa Phi; Min-Ji Shin; Seulah Lee; Jae Eun So; Ji Hee Kim; Sung-Suk Suh; Man Hyung Koo; Seung Chul Shin; Jin-Hyoung Kim; Jun Hyuck Lee; Ui Joung Youn
Journal:  Molecules       Date:  2022-04-06       Impact factor: 4.411

Review 5.  Anticancer Potential of Lichens' Secondary Metabolites.

Authors:  Zuzana Solárová; Alena Liskova; Marek Samec; Peter Kubatka; Dietrich Büsselberg; Peter Solár
Journal:  Biomolecules       Date:  2020-01-05
  5 in total

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