Literature DB >> 19481244

Comparison of the quality of life of early and advanced stage ovarian cancer survivors.

Kristina L Mirabeau-Beale1, Alice B Kornblith, Richard T Penson, Hang Lee, Annekathryn Goodman, Susana M Campos, Linda Duska, Lauren Pereira, Jessica Bryan, Ursula A Matulonis.   

Abstract

OBJECTIVE: The objective of this study was to compare the long-term adjustment and QOL of early and advanced stage ovarian cancer survivors (OCS).
METHODS: Early and advanced OCS >3 years from diagnosis with no evidence of recurrent cancer were interviewed. The following surveys were administered: EORTC QLQ-C30 (overall QOL) and QLQ-OV28 (ovarian specific issues), MHI-17 (anxiety, depression and global well-being), CALGB sexual functioning, FACT Fatigue, Beck's Hopelessness Scale, Fear of Recurrence (FOR), PCL-C post-traumatic stress disorder (PTSD), Unmet Needs, FACT-Spirituality (FACT-Sp), complementary therapy (CAM use), and MOS Social Support Survey (MOS). The results of the surveys were compared between the early and advanced stage groups.
RESULTS: 42 advanced and 58 early stage patients were interviewed. The majority of survivors scored above the medical outpatient norm for emotional status (71% of early stage and 64% of advanced stage survivors). Overall QOL, fatigue, hopelessness, spirituality, social support, degree to which unmet needs were met and use of complementary therapy, did not differ between the two groups. No advanced stage OCS had diagnosable PTSD scores, while 6.9% of early stage survivors had scores indicative of PTSD. Decreased sexual interest attributed to cancer and anxiety when getting CA-125 testing were of concern for both groups. OCS used on average 5 CAM to improve their QOL.
CONCLUSION: Regardless of staging, OCS experience similarly overall positive QOL and adjustment, though PTSD, sexual problems and fear of recurrence are still important for some survivors.

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Mesh:

Year:  2009        PMID: 19481244     DOI: 10.1016/j.ygyno.2009.05.009

Source DB:  PubMed          Journal:  Gynecol Oncol        ISSN: 0090-8258            Impact factor:   5.482


  35 in total

Review 1.  Health-related quality of life in ovarian cancer patients and its impact on clinical management.

Authors:  Dana M Chase; Lari Wenzel
Journal:  Expert Rev Pharmacoecon Outcomes Res       Date:  2011-08       Impact factor: 2.217

2.  A new index of priority symptoms in advanced ovarian cancer.

Authors:  Sally E Jensen; Sarah K Rosenbloom; Jennifer L Beaumont; Amy Abernethy; Paul B Jacobsen; Karen Syrjala; David Cella
Journal:  Gynecol Oncol       Date:  2010-11-13       Impact factor: 5.482

Review 3.  A systematic review of ovarian cancer and fear of recurrence.

Authors:  Melissa Ozga; Carol Aghajanian; Shannon Myers-Virtue; Glynnis McDonnell; Sabrina Jhanwar; Shira Hichenberg; Isabel Sulimanoff
Journal:  Palliat Support Care       Date:  2015-03-02

4.  Screening for sexual health concerns in survivors of gynecological cancer.

Authors:  Karen Roberts; Travis Chong; Emma Hollands; Jason Tan; Ganendra Raj Kader Ali Mohan; Paul A Cohen
Journal:  Support Care Cancer       Date:  2019-05-18       Impact factor: 3.603

5.  Sensitivity of Preference-Based Quality-of-Life Measures for Economic Evaluations in Early-Stage Melanoma.

Authors:  Mbathio Dieng; Nadine A Kasparian; Anne E Cust; Daniel S J Costa; Anh Tran; Phyllis N Butow; Scott W Menzies; Graham J Mann; Rachael L Morton
Journal:  JAMA Dermatol       Date:  2018-01-01       Impact factor: 10.282

Review 6.  Fear of cancer recurrence in adult cancer survivors: a systematic review of quantitative studies.

Authors:  Sébastien Simard; Belinda Thewes; Gerry Humphris; Mélanie Dixon; Ceara Hayden; Shab Mireskandari; Gozde Ozakinci
Journal:  J Cancer Surviv       Date:  2013-03-10       Impact factor: 4.442

7.  Faith and mental health in an oncology population.

Authors:  Janice Bell Meisenhelder; Nancy J Schaeffer; Jerry Younger; Marisa Lauria
Journal:  J Relig Health       Date:  2013-06

8.  Psychological Problems Experienced by Women with Gynecological Cancer and How They Cope with It: A Phenomenological Study in Turkey.

Authors:  Sengül Yaman; Sultan Ayaz
Journal:  Health Soc Work       Date:  2016-08-01

9.  Symptom clusters and quality of life in older adult breast cancer survivors.

Authors:  Rachel A Roiland; Susan M Heidrich
Journal:  Oncol Nurs Forum       Date:  2011-11       Impact factor: 2.172

10.  Quality of life trajectories after diagnosis of gynecologic cancer: a theoretically based approach.

Authors:  Brian D Gonzalez; Sharon L Manne; Jerod Stapleton; Shannon Myers-Virtue; Melissa Ozga; David Kissane; Carolyn Heckman; Mark Morgan
Journal:  Support Care Cancer       Date:  2016-10-19       Impact factor: 3.603

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