| Literature DB >> 19481231 |
Elfita Elfita1, Muharni Muharni, Madyawati Latief, Darwati Darwati, Ari Widiyantoro, Supriyatna Supriyatna, Husein H Bahti, Dachriyanus Dachriyanus, Paul Cos, Louis Maes, Kenne Foubert, Sandra Apers, Luc Pieters.
Abstract
Phytochemical investigations of four Garcinia spp. from Indonesia, i.e. Garcinia griffithii T. Anderson, Garcinia celebica L., Garcinia cornea L. and Garcinia cymosa K. Schum (Clusiaceae), have resulted in the isolation of a xanthone, 1,5-dihydroxy-3,6-dimethoxy-2,7-diprenylxanthone, 1,7-dihydroxyxanthone, isoxanthochymol, beta-sitosterol-3-O-beta-D-glucoside and stigmasterol-3-O-beta-D-glucoside from the stem bark of G. griffithii; friedelin and 3beta-hydroxy-23-oxo-9,16-lanostadien-26-oic acid or garcihombronane D from leaves of G. celebica; 23-hydroxy-3-oxo-cycloart-24-en-26-oic acid and epicatechin from stem bark of G. cornea; (+/-)-morelloflavone, morelloflavone-7-O-beta-D-glucoside or fukugiside, the triterpene 3beta-hydroxy-5-glutinen-28-oic acid and canophyllol from stem bark of G. cymosa. The xanthone and garcihombronane D displayed a selective activity against Plasmodium falciparum; isoxanthochymol and the triterpene beta-hydroxy-5-glutinen-28-oic acid a broad but non-selective antiprotozoal activity.Entities:
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Year: 2009 PMID: 19481231 DOI: 10.1016/j.phytochem.2009.04.024
Source DB: PubMed Journal: Phytochemistry ISSN: 0031-9422 Impact factor: 4.072