Literature DB >> 19481231

Antiplasmodial and other constituents from four Indonesian Garcinia spp.

Elfita Elfita1, Muharni Muharni, Madyawati Latief, Darwati Darwati, Ari Widiyantoro, Supriyatna Supriyatna, Husein H Bahti, Dachriyanus Dachriyanus, Paul Cos, Louis Maes, Kenne Foubert, Sandra Apers, Luc Pieters.   

Abstract

Phytochemical investigations of four Garcinia spp. from Indonesia, i.e. Garcinia griffithii T. Anderson, Garcinia celebica L., Garcinia cornea L. and Garcinia cymosa K. Schum (Clusiaceae), have resulted in the isolation of a xanthone, 1,5-dihydroxy-3,6-dimethoxy-2,7-diprenylxanthone, 1,7-dihydroxyxanthone, isoxanthochymol, beta-sitosterol-3-O-beta-D-glucoside and stigmasterol-3-O-beta-D-glucoside from the stem bark of G. griffithii; friedelin and 3beta-hydroxy-23-oxo-9,16-lanostadien-26-oic acid or garcihombronane D from leaves of G. celebica; 23-hydroxy-3-oxo-cycloart-24-en-26-oic acid and epicatechin from stem bark of G. cornea; (+/-)-morelloflavone, morelloflavone-7-O-beta-D-glucoside or fukugiside, the triterpene 3beta-hydroxy-5-glutinen-28-oic acid and canophyllol from stem bark of G. cymosa. The xanthone and garcihombronane D displayed a selective activity against Plasmodium falciparum; isoxanthochymol and the triterpene beta-hydroxy-5-glutinen-28-oic acid a broad but non-selective antiprotozoal activity.

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Year:  2009        PMID: 19481231     DOI: 10.1016/j.phytochem.2009.04.024

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  4 in total

1.  Three new xanthones from the leaves of Garcinia lancilimba.

Authors:  Yating Sun; Dahong Li; Cuicui Jia; Chunmei Xue; Jiao Bai; Zhanlin Li; Huiming Hua
Journal:  J Nat Med       Date:  2015-12-08       Impact factor: 2.343

2.  Gastroprotective effects of extracts and guttiferone A isolated from Garcinia achachairu Rusby (Clusiaceae) against experimentally induced gastric lesions in mice.

Authors:  Rivaldo Niero; Marlova Manhabosco Dal Molin; Suellen Silva; Natália Santos Damian; Láis Orlof Maia; Franco Delle Monache; Valdir Cechinel Filho; Sérgio Faloni de Andrade
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2012-08-29       Impact factor: 3.000

3.  IN VIVO CARBON TETRACHLORIDE-INDUCED HEPATOPROTECTIVE AND IN VITRO CYTOTOXIC ACTIVITIES OF GARCINIA HOMBRONIANA (SEASHORE MANGOSTEEN).

Authors:  Nargis Jamila; Naeem Khan; Amir Atlas Khan; Imran Khan; Sadiq Noor Khan; Zainal Amiruddin Zakaria; Melati Khairuddean; Hasnah Osman; Kyong Su Kim
Journal:  Afr J Tradit Complement Altern Med       Date:  2017-01-13

4.  Cytotoxic Effects of Pinnatane A Extracted from Walsura pinnata (Meliaceae) on Human Liver Cancer Cells.

Authors:  Nurhisyam Zakaria; Mohamad Azrul Mahdzir; Mahfuzah Yusoff; Norhafiza Mohd Arshad; Khalijah Awang; Noor Hasima Nagoor
Journal:  Molecules       Date:  2018-10-23       Impact factor: 4.411

  4 in total

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