Literature DB >> 19480052

Dynamics of excitable elements with time-delayed coupling.

S Rüdiger1, L Schimansky-Geier.   

Abstract

Motivated by recent experiments on intracellular calcium release we study the effects of different types of coupling on the dynamics of arrays of excitable elements. We intend to find a mechanism that produces a sustained activity of the elements following a spike. While instantaneous diffusive coupling does not exhibit this property, we show that, for a coupling term with temporal delay, signals from adjacent elements can serve as mutual excitations and thus prolong the duration of the signal. We propose that time delayed coupling is generated by diffusion between isolated clusters of calcium channels. Our model could thus provide an explanation for two different release modes observed in the Ca2+ system.

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Year:  2009        PMID: 19480052     DOI: 10.1016/j.jtbi.2009.01.030

Source DB:  PubMed          Journal:  J Theor Biol        ISSN: 0022-5193            Impact factor:   2.691


  3 in total

1.  Control of bursting behavior in neurons by autaptic modulation.

Authors:  Lei Wang; Yanjun Zeng
Journal:  Neurol Sci       Date:  2013-04-18       Impact factor: 3.307

2.  Calcium waves in a grid of clustered channels with synchronous IP3 binding and unbinding.

Authors:  M Rückl; S Rüdiger
Journal:  Eur Phys J E Soft Matter       Date:  2016-11-17       Impact factor: 1.890

3.  Calcium domains around single and clustered IP3 receptors and their modulation by buffers.

Authors:  S Rüdiger; Ch Nagaiah; G Warnecke; J W Shuai
Journal:  Biophys J       Date:  2010-07-07       Impact factor: 4.033

  3 in total

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