AIM: To define the Y-chromosomal genetic structure in a sample of Atayal men from Taiwan. METHODS: Buccal swab samples were collected from 170 unrelated healthy male volunteers from Taiwanese aboriginal Atayal population. Genomic DNA was extracted and 17 Y chromosome-specific short tandem repeat loci (DYS456, DYS389I, DYS390, DYS389II, DYS458, DYS19, DYS385a/b, DYS393, DYS391, DYS439, DYS635, DYS392, Y GATA H4, DYS437, DYS438, and DYS448) were analyzed using the AmpFlSTR Yfiler Polymerase Chain Reaction Amplification Kit. RESULTS: A total of 99 different haplotypes were identified, 69 (69.7%) of which were unique. Total haplotype diversity was 0.9887. The most common haplotype was shared by 9 individuals in the study sample. Gene diversities ranged from 0.0574 for DYS438 to 0.6749 for DYS456. CONCLUSION: Our results will help provide the molecular genetic evidence for human settlement of the Pacific.
AIM: To define the Y-chromosomal genetic structure in a sample of Atayal men from Taiwan. METHODS: Buccal swab samples were collected from 170 unrelated healthy male volunteers from Taiwanese aboriginal Atayal population. Genomic DNA was extracted and 17 Y chromosome-specific short tandem repeat loci (DYS456, DYS389I, DYS390, DYS389II, DYS458, DYS19, DYS385a/b, DYS393, DYS391, DYS439, DYS635, DYS392, Y GATA H4, DYS437, DYS438, and DYS448) were analyzed using the AmpFlSTR Yfiler Polymerase Chain Reaction Amplification Kit. RESULTS: A total of 99 different haplotypes were identified, 69 (69.7%) of which were unique. Total haplotype diversity was 0.9887. The most common haplotype was shared by 9 individuals in the study sample. Gene diversities ranged from 0.0574 for DYS438 to 0.6749 for DYS456. CONCLUSION: Our results will help provide the molecular genetic evidence for human settlement of the Pacific.
Authors: M Kayser; M Krawczak; L Excoffier; P Dieltjes; D Corach; V Pascali; C Gehrig; L F Bernini; J Jespersen; E Bakker; L Roewer; P de Knijff Journal: Am J Hum Genet Date: 2001-03-16 Impact factor: 11.025
Authors: B Su; L Jin; P Underhill; J Martinson; N Saha; S T McGarvey; M D Shriver; J Chu; P Oefner; R Chakraborty; R Deka Journal: Proc Natl Acad Sci U S A Date: 2000-07-18 Impact factor: 11.205
Authors: Matthew E Hurles; Jayne Nicholson; Elena Bosch; Colin Renfrew; Bryan C Sykes; Mark A Jobling Journal: Genetics Date: 2002-01 Impact factor: 4.562
Authors: C Capelli; J F Wilson; M Richards; M P Stumpf; F Gratrix; S Oppenheimer; P Underhill; V L Pascali; T M Ko; D B Goldstein Journal: Am J Hum Genet Date: 2001-01-22 Impact factor: 11.025
Authors: J Y Chu; W Huang; S Q Kuang; J M Wang; J J Xu; Z T Chu; Z Q Yang; K Q Lin; P Li; M Wu; Z C Geng; C C Tan; R F Du; L Jin Journal: Proc Natl Acad Sci U S A Date: 1998-09-29 Impact factor: 11.205