Literature DB >> 19479965

The collagen receptor DDR2 is expressed during early cardiac development.

Edie C Goldsmith1, Xiadong Zhang, James Watson, Josh Hastings, Jay D Potts.   

Abstract

Discoidin Domain Receptor 2 (DDR2) is a receptor tyrosine kinase which has been shown to regulate cell migration upon binding its ligand, collagen. Expression studies determined that DDR2 mRNA and protein are present in the atrioventricular canal during epithelial-mesenchymal transformation (EMT) and the receptor is expressed in both activated endothelial and migrating mesenchymal cells in vivo.

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Year:  2010        PMID： 19479965      PMCID： PMC6733606          DOI： 10.1002/ar.20922

Source DB:  PubMed          Journal:  Anat Rec (Hoboken)        ISSN： 1932-8486            Impact factor:   2.064


  29 in total

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