Literature DB >> 1947817

Molecular biology of antigenic variation in Lyme borreliosis and relapsing fever: a comparative analysis.

A G Barbour1.   

Abstract

Lyme borreliosis and relapsing fever are human diseases caused by different members of the genus Borrelia. Antigenic variation has been a well-known feature of the pathogenesis of relapsing fever for decades. More recently it has been recognized that Borrelia burgdorferi, the agent of Lyme borreliosis, also can vary its surface antigens. In this review the biology and molecular biology of antigenic variation of the pathogens in these two disorders are compared.

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Year:  1991        PMID: 1947817

Source DB:  PubMed          Journal:  Scand J Infect Dis Suppl        ISSN: 0300-8878


  7 in total

1.  Antigenic stability of Borrelia burgdorferi during chronic infections of immunocompetent mice.

Authors:  S W Barthold
Journal:  Infect Immun       Date:  1993-12       Impact factor: 3.441

2.  Molecular cloning, expression, and DNA sequence analysis of the gene that encodes the 16-kilodalton outer membrane lipoprotein of Serpulina hyodysenteriae.

Authors:  W Thomas; R Sellwood
Journal:  Infect Immun       Date:  1993-03       Impact factor: 3.441

3.  Polymorphism in ospC gene of Borrelia burgdorferi and immunoreactivity of OspC protein: implications for taxonomy and for use of OspC protein as a diagnostic antigen.

Authors:  M Theisen; B Frederiksen; A M Lebech; J Vuust; K Hansen
Journal:  J Clin Microbiol       Date:  1993-10       Impact factor: 5.948

4.  Genetic stability of Borrelia burgdorferi recovered from chronically infected immunocompetent mice.

Authors:  D H Persing; D Mathiesen; D Podzorski; S W Barthold
Journal:  Infect Immun       Date:  1994-08       Impact factor: 3.441

Review 5.  Lyme Disease Pathogenesis.

Authors:  Jenifer Coburn; Brandon Garcia; Linden T Hu; Mollie W Jewett; Peter Kraiczy; Steven J Norris; Jon Skare
Journal:  Curr Issues Mol Biol       Date:  2020-12-23       Impact factor: 2.081

6.  Antibody-resistant mutants of Borrelia burgdorferi: in vitro selection and characterization.

Authors:  A Sădziene; P A Rosa; P A Thompson; D M Hogan; A G Barbour
Journal:  J Exp Med       Date:  1992-09-01       Impact factor: 14.307

7.  Multiscale Immune Selection and the Transmission-Diversity Feedback in Antigenically Diverse Pathogen Systems.

Authors:  Thomas Holding; John Joseph Valletta; Mario Recker
Journal:  Am Nat       Date:  2018-09-05       Impact factor: 3.926

  7 in total

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