| Literature DB >> 19477560 |
David Pace1, Andrew J Pollard, Nancy E Messonier.
Abstract
Neisseria meningitidis is an important cause of bacterial meningitis and septicaemia with most disease caused by meningococci bearing serogroups A, B, C, Y and W-135 polysaccharides. Monovalent serogroup C conjugate vaccines have become established in the immunisation programmes in many countries and the first quadrivalent meningococcal vaccine, containing the polysaccharides from 4 of the serogroups A, C, Y and W-135 meningococci conjugated to a protein carrier was licensed in the US in 2005. This vaccine and others in development offer the potential to broaden population protection against meningococcal disease.Entities:
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Year: 2009 PMID: 19477560 DOI: 10.1016/j.vaccine.2009.05.003
Source DB: PubMed Journal: Vaccine ISSN: 0264-410X Impact factor: 3.641