| Literature DB >> 19475600 |
Chun-Hua Lu1, Huang-Hao Yang, Chun-Ling Zhu, Xi Chen, Guo-Nan Chen.
Abstract
Sensitive platform: The use of graphene oxide (GO) as a platform for the sensitive and selective detection of DNA and proteins is presented. The interaction of GO and dye-labeled single-stranded DNA leads to quenching of the dye fluorescence. Conversely, the presence of a target DNA or protein leads to the binding of the dye-labeled DNA and target, releasing the DNA from GO, thereby restoring the dye fluorescence (see picture).Entities:
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Year: 2009 PMID: 19475600 DOI: 10.1002/anie.200901479
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN: 1433-7851 Impact factor: 15.336