BACKGROUND AND PURPOSE: We determined in a population-based study whether sleep duration was associated with an increased risk of incident dementia. METHODS: In a population-based study in central Spain, participants were evaluated at baseline and 3 years later. Baseline demographic variables were recorded and participants indicated their daily sleep duration as the sum of night-time sleep and daytime napping. The average daily total sleep duration was grouped into five categories: < or = 5 (short sleepers), 6, 7 (reference), 8, and > or = 9 h (long sleepers). We identified all cases with incident dementia, diagnosed using DSM-IV criteria. RESULTS: Three thousand two hundred eighty six participants with baseline information about sleep duration had a median duration of follow-up of 3.2 years. There were 140 incident cases of dementia. The relative risks (RR) for short sleepers and for long sleepers were 2.36 (95% CI = 1.07-5.21, P = 0.03) and 2.40 (95% CI = 1.20-4.81, P = 0.01), respectively. After adjustment for potential confounders, the RR was only marginally increased for short sleepers (1.87, 95% CI = 0.85-4.15, P = 0.12) but remained increased for long sleepers (2.18; 95% CI = 1.09-4.37, P = 0.03). CONCLUSIONS: Prolonged sleep duration (night-time sleep and daytime napping) may be associated with an increased risk of dementia.
BACKGROUND AND PURPOSE: We determined in a population-based study whether sleep duration was associated with an increased risk of incident dementia. METHODS: In a population-based study in central Spain, participants were evaluated at baseline and 3 years later. Baseline demographic variables were recorded and participants indicated their daily sleep duration as the sum of night-time sleep and daytime napping. The average daily total sleep duration was grouped into five categories: < or = 5 (short sleepers), 6, 7 (reference), 8, and > or = 9 h (long sleepers). We identified all cases with incident dementia, diagnosed using DSM-IV criteria. RESULTS: Three thousand two hundred eighty six participants with baseline information about sleep duration had a median duration of follow-up of 3.2 years. There were 140 incident cases of dementia. The relative risks (RR) for short sleepers and for long sleepers were 2.36 (95% CI = 1.07-5.21, P = 0.03) and 2.40 (95% CI = 1.20-4.81, P = 0.01), respectively. After adjustment for potential confounders, the RR was only marginally increased for short sleepers (1.87, 95% CI = 0.85-4.15, P = 0.12) but remained increased for long sleepers (2.18; 95% CI = 1.09-4.37, P = 0.03). CONCLUSIONS: Prolonged sleep duration (night-time sleep and daytime napping) may be associated with an increased risk of dementia.
Authors: Calliope Holingue; Alexandra Wennberg; Slava Berger; Vsevolod Y Polotsky; Adam P Spira Journal: Metabolism Date: 2018-02-01 Impact factor: 8.694
Authors: Pamela L Lutsey; Jeffrey R Misialek; Thomas H Mosley; Rebecca F Gottesman; Naresh M Punjabi; Eyal Shahar; Richard MacLehose; Rachel P Ogilvie; David Knopman; Alvaro Alonso Journal: Alzheimers Dement Date: 2017-07-21 Impact factor: 21.566
Authors: Brian S Mohlenhoff; Philip S Insel; R Scott Mackin; Thomas C Neylan; Derek Flenniken; Rachel Nosheny; Anne Richards; Paul Maruff; Michael W Weiner Journal: J Clin Sleep Med Date: 2018-09-15 Impact factor: 4.062
Authors: Alberto R Ramos; Wassim Tarraf; Martha Daviglus; Sonia Davis; Linda C Gallo; Yasmin Mossavar-Rahmani; Frank J Penedo; Susan Redline; Tatjana Rundek; Ralph L Sacco; Daniela Sotres-Alvarez; Clinton B Wright; Phyllis C Zee; Hector M González Journal: Sleep Date: 2016-10-01 Impact factor: 5.849