Cisplatin ototoxicity in children: implications for primary care providers.

This integrative literature review examines the long-term sensorineural hearing loss associated with cisplatin chemotherapy treatment in children with cancer. CINAHL, PsychInfo, Medline, Google Scholar, and Google databases were searched for research related to cisplatin-induced ototoxicity. The characteristics, prevalence, and underlying mechanisms of cisplatin ototoxicity are discussed. Primary care implications, including how and when to monitor the hearing of childhood cancer survivors, ways to provide family support, and education about the significance of hearing losses, and an overview of the management for hearing impairments are presented.