Iron(III)-catalyzed and air-mediated tandem reaction of aldehydes, alkynes and amines: an efficient approach to substituted quinolines.

Economic and practical advantages are offered by the iron(III)-catalyzed and air-mediated tandem coupling/hydroarylation/dehydrogenation of simple readily available aldehydes, alkynes, and amines for the synthesis of 2, 4-disubstituted quinolines (see scheme).