| Literature DB >> 194703 |
Abstract
Two apparently distinct species of cyclic AMP-dependent protein kinase appear during the first 1-2 hr of development in Dictyostelium discoideum; no such activity can be detected in vegetative cell extracts. These two kinases are similar in properties to the type I and II cyclic AMP-dependent protein kinases found in a number of mammalian tissues. Their time of appearance supports the idea that one or both mediate the effects of cyclic AMP on gene expression early in Dictyostelium development.Entities:
Mesh:
Substances:
Year: 1977 PMID: 194703 DOI: 10.1016/0092-8674(77)90328-2
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582