The antibiotic challenge: changing clinical management of infections.

Resistance is one of many reasons why antibiotic therapy can be ineffective. Efforts to forestall further development of antimicrobial resistance include judicial prescribing of antibiotics, implementing infection-control measures, and developing institutional stewardship of antimicrobial agents. This article, the third and final in a series on antibiotic resistance, discusses selected common infections that have changing epidemiology and/or for which the recommended evaluation and treatment guidelines have been updated.