Literature DB >> 19467612

The history of doping and growth hormone abuse in sport.

Richard I G Holt1, Ioulietta Erotokritou-Mulligan, Peter H Sönksen.   

Abstract

The earliest records of doping in sport come from the Ancient Olympics games when athletes are reported to have taken figs to improve their performance. With the advent of modern pharmacology in the 19th century, many athletes began to experiment with cocktails of drugs to improve strength and overcome fatigue. As this practice was not illegal, there are good records of the lengths athletes would go to in order to win. Alongside the benefits, came the dangers and following several fatalities, a code to ban performance enhancing drugs was gradually developed. Growth hormone was first isolated from the human pituitary gland in the 1950s. Its anabolic effects were soon recognised and athletes had begun to abuse it by the early 1980s, at least a decade before it was used therapeutically by adult endocrinologists. A number of high profile athletes have admitted using growth hormone. Detection of its abuse has been challenging and the lack of an effective test has undoubtedly encouraged its abuse. Only now are methodologies being developed that should stem this tide.

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Year:  2009        PMID: 19467612     DOI: 10.1016/j.ghir.2009.04.009

Source DB:  PubMed          Journal:  Growth Horm IGF Res        ISSN: 1096-6374            Impact factor:   2.372


  10 in total

1.  Academic doping or Viagra for the brain? The history of recreational drug use and pharmacological enhancement can provide insight into these uses of neuropharmaceuticals.

Authors:  Jayne C Lucke; Stephanie K Bell; Bradley J Partridge; Wayne D Hall
Journal:  EMBO Rep       Date:  2011-02-11       Impact factor: 8.807

Review 2.  Idiopathic adult growth hormone deficiency.

Authors:  Shlomo Melmed
Journal:  J Clin Endocrinol Metab       Date:  2013-03-28       Impact factor: 5.958

3.  Availability and quality of illegitimate somatropin products obtained from the Internet.

Authors:  Róbert György Vida; András Fittler; Ivett Mikulka; Eszter Ábrahám; Viktor Sándor; Ferenc Kilár; Lajos Botz
Journal:  Int J Clin Pharm       Date:  2016-11-25

Review 4.  Ethical Concerns in Sport: When the Will to Win Exceed the Spirit of Sport.

Authors:  Nancy Vargas-Mendoza; Tomás Fregoso-Aguilar; Eduardo Madrigal-Santillán; Ángel Morales-González; José A Morales-González
Journal:  Behav Sci (Basel)       Date:  2018-09-03

Review 5.  Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males.

Authors:  Deepankar K Sinha; Adithya Balasubramanian; Alexander J Tatem; Jorge Rivera-Mirabal; Justin Yu; Jason Kovac; Alexander W Pastuszak; Larry I Lipshultz
Journal:  Transl Androl Urol       Date:  2020-03

6.  Doping Knowledge, Attitude and Practice of Pharmacists in Dessie, Northeast Ethiopia.

Authors:  Haftom Gebregergs Hailu; Mengistie Yirsaw Gobezie; Abdu Tuha; Ruth Mulugeta; Solomon Ahmed Mohammed
Journal:  Integr Pharm Res Pract       Date:  2021-05-31

7.  The Proteomic Signature of Recombinant Growth Hormone in Recreational Athletes.

Authors:  Max Esefeld; Antoni Pastor; Rafael de la Torre; Osquel Barroso; Reid Aikin; Hina Sarwath; Rudolf Engelke; Frank Schmidt; Karsten Suhre
Journal:  J Endocr Soc       Date:  2021-11-02

8.  Early and extraordinary peaks in physical performance come with a longevity cost.

Authors:  Paul L van de Vijver; David van Bodegom; Rudi G J Westendorp
Journal:  Aging (Albany NY)       Date:  2016-08       Impact factor: 5.682

9.  Effects of Growth Hormone on Cardiac Remodeling During Resistance Training in Rats.

Authors:  Adriana Junqueira; Antônio Carlos Cicogna; Letícia Estevam Engel; Maiara Almeida Aldá; Loreta Casquel de Tomasi; Rogério Giuffrida; Inês Cristina Giometti; Ana Paula Coelho Figueira Freire; Andreo Fernando Aguiar; Francis Lopes Pacagnelli
Journal:  Arq Bras Cardiol       Date:  2015-12-08       Impact factor: 2.000

10.  Potential propensity of traditional herbal materials ingested by collegiate athletes in South China for their consuming health care.

Authors:  Yue-Quan Qin; Chun-Song Cheng; Ying Jiang; Wei Qi; Bin Zhang; Dong-Yi Wei
Journal:  Medicine (Baltimore)       Date:  2021-11-05       Impact factor: 1.817

  10 in total

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