Literature DB >> 19464602

Melanoma and immunotherapy.

Alexander M M Eggermont1, Dirk Schadendorf.   

Abstract

About 20% of all primary melanomas will spread. The likelihood of metastatic behavior correlates with prognostic factors such as tumor thickness, mitotic index, presence of ulceration, lymphocyte infiltration, age, gender, and anatomic site. Immunotherapies are developed for melanoma patients in stage IV who have distant metastases and in stage II to III patients in the adjuvant micrometastatic setting, where only a fraction of patients have widespread (microscopic) disease.

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Year:  2009        PMID: 19464602     DOI: 10.1016/j.hoc.2009.03.009

Source DB:  PubMed          Journal:  Hematol Oncol Clin North Am        ISSN: 0889-8588            Impact factor:   3.722


  11 in total

Review 1.  Melanoma: new insights and new therapies.

Authors:  Vasiliki A Nikolaou; Alexander J Stratigos; Keith T Flaherty; Hensin Tsao
Journal:  J Invest Dermatol       Date:  2012-01-05       Impact factor: 8.551

2.  Differential Antitumor Effects of IgG and IgM Monoclonal Antibodies and Their Synthetic Complementarity-Determining Regions Directed to New Targets of B16F10-Nex2 Melanoma Cells.

Authors:  Andrey S Dobroff; Elaine G Rodrigues; Maria A Juliano; Dayson M Friaça; Ernesto S Nakayasu; Igor C Almeida; Renato A Mortara; Jacqueline F Jacysyn; Gustavo P Amarante-Mendes; Walter Magliani; Stefania Conti; Luciano Polonelli; Luiz R Travassos
Journal:  Transl Oncol       Date:  2010-08-01       Impact factor: 4.243

Review 3.  Immunologic functions as prognostic indicators in melanoma.

Authors:  Marna G Bouwhuis; Timo L M ten Hagen; Alexander M M Eggermont
Journal:  Mol Oncol       Date:  2011-02-03       Impact factor: 6.603

4.  Targeted therapy and immunotherapy in advanced melanoma: an evolving paradigm.

Authors:  Muhammad Khattak; Rosalie Fisher; Samra Turajlic; James Larkin
Journal:  Ther Adv Med Oncol       Date:  2013-03       Impact factor: 8.168

5.  Melanoma: a model for testing new agents in combination therapies.

Authors:  Paolo A Ascierto; Howard Z Streicher; Mario Sznol
Journal:  J Transl Med       Date:  2010-04-20       Impact factor: 5.531

6.  A Clinical Study of a Cell-Based MAGE-A3 Active Immunotherapy in Advanced Melanoma Patients.

Authors:  Vincenzo Russo; Francesca Lunghi; Raffaella Fontana; Marco Bregni
Journal:  J Cancer       Date:  2011-06-01       Impact factor: 4.207

7.  NF‑κB inhibition is associated with OPN/MMP‑9 downregulation in cutaneous melanoma.

Authors:  Claudio Guarneri; Valentina Bevelacqua; Jerry Polesel; Luca Falzone; Patrizia S Cannavò; Demetrios A Spandidos; Grazia Malaponte; Massimo Libra
Journal:  Oncol Rep       Date:  2017-01-10       Impact factor: 3.906

Review 8.  Dabrafenib and its potential for the treatment of metastatic melanoma.

Authors:  Alexander M Menzies; Georgina V Long; Rajmohan Murali
Journal:  Drug Des Devel Ther       Date:  2012-12-11       Impact factor: 4.162

9.  High-Dose Interleukin-2 (HD IL-2) Therapy Should Be Considered for Treatment of Patients with Melanoma Brain Metastases.

Authors:  Melinda B Chu; Mark J Fesler; Eric S Armbrecht; Scott W Fosko; Eddy Hsueh; John M Richart
Journal:  Chemother Res Pract       Date:  2013-05-13

10.  Molecular targeted therapies in metastatic melanoma.

Authors:  Rima Chakraborty; Carilyn N Wieland; Nneka I Comfere
Journal:  Pharmgenomics Pers Med       Date:  2013-06-07
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