Literature DB >> 19464424

Efficacy and safety of incretin-based therapies in patients with type 2 diabetes mellitus.

Matthew P Gilbert1, Richard E Pratley.   

Abstract

This article aims to provide an overview of efficacy and safety data on glucagon-like peptide-1 (GLP-1) receptor agonists and dipeptidyl peptidase-4 (DPP-4) inhibitors in the treatment of type 2 diabetes mellitus. Our goal is to differentiate the clinical profiles of GLP-1 receptor agonists and DPP-4 inhibitors, as well as the individual agents within each class. Additionally, we examine the utility of GLP-1 receptor agonists and DPP-4 inhibitors as these agents may be applied at different stages of type 2 diabetes therapy and discuss recently published clinical findings and their implications for treatment.

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Year:  2009        PMID: 19464424     DOI: 10.1016/j.amjmed.2009.03.013

Source DB:  PubMed          Journal:  Am J Med        ISSN: 0002-9343            Impact factor:   4.965


  13 in total

Review 1.  Pharmacology of dipeptidyl peptidase-4 inhibitors: similarities and differences.

Authors:  Roberta Baetta; Alberto Corsini
Journal:  Drugs       Date:  2011-07-30       Impact factor: 9.546

Review 2.  What are the best options for controlling prandial glycemia?

Authors:  Stephen Clement
Journal:  Curr Diab Rep       Date:  2009-10       Impact factor: 4.810

3.  Identification of Novel, Structurally Diverse, Small Molecule Modulators of GPR119.

Authors:  Ainhoa Nieto; Virneliz Fernández-Vega; Timothy P Spicer; Emmanuel Sturchler; Pramisha Adhikari; Nicole Kennedy; Sean Mandat; Peter Chase; Louis Scampavia; Thomas Bannister; Peter Hodder; Patricia H McDonald
Journal:  Assay Drug Dev Technol       Date:  2018-07       Impact factor: 1.738

Review 4.  Mechanisms of current therapies for diabetes mellitus type 2.

Authors:  Peter M Thulé
Journal:  Adv Physiol Educ       Date:  2012-12       Impact factor: 2.288

5.  Profibrinolytic, antithrombotic, and antiinflammatory effects of an insulin-sensitizing strategy in patients in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial.

Authors:  Burton E Sobel; Regina M Hardison; Saul Genuth; Maria M Brooks; Robert D McBane; David J Schneider; Richard E Pratley; Kurt Huber; Robert Wolk; Ashok Krishnaswami; Robert L Frye
Journal:  Circulation       Date:  2011-07-18       Impact factor: 29.690

6.  [Incretins: do they exert cardiovascular effects?].

Authors:  Baptist Gallwitz
Journal:  Herz       Date:  2010-05       Impact factor: 1.443

Review 7.  Incretin agents in type 2 diabetes.

Authors:  Stuart A Ross; Jean-Marie Ekoé
Journal:  Can Fam Physician       Date:  2010-07       Impact factor: 3.275

8.  Further improvement in postprandial glucose control with addition of exenatide or sitagliptin to combination therapy with insulin glargine and metformin: a proof-of-concept study.

Authors:  Sabine Arnolds; Sibylle Dellweg; Janina Clair; Marie-Paule Dain; Michael A Nauck; Klaus Rave; Christoph Kapitza
Journal:  Diabetes Care       Date:  2010-03-31       Impact factor: 17.152

9.  Preclinical and Clinical Data on Extraglycemic Effects of GLP-1 Receptor Agonists.

Authors:  Baptist Gallwitz
Journal:  Rev Diabet Stud       Date:  2009-12-30

10.  Minimizing the risk of hypoglycemia with vildagliptin: Clinical experience, mechanistic basis, and importance in type 2 diabetes management.

Authors:  Sylvie Dejager; Anja Schweizer
Journal:  Diabetes Ther       Date:  2011-02-08       Impact factor: 2.945

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