| Literature DB >> 19463693 |
Liliang Huang1, Yanhong Sun, Hua Zhu, Yuanqing Zhang, Jia Xu, Yu-Mei Shen.
Abstract
Two series of novel bile acid tridentate conjugates with different linkers were synthesized and characterized, and their biological activities in vitro were evaluated. The procedure was straightforward and efficient to be carried out with high overall yield. The antimicrobial activity of the synthesized compounds against Saccharomyces cerevisiae, Aspergillus niger, Escherichia coli and Staphylococcus aureus was investigated in vitro. The best activity of minimal inhibitory concentrations (MICs) for 1c, 1c', 2c and 2c' against S. cerevisiae was up to 0.125 microg/mL.Entities:
Mesh：
Substances：
Year: 2009 PMID： 19463693 DOI： 10.1016/j.steroids.2009.03.005
Source DB: PubMed Journal: Steroids ISSN： 0039-128X Impact factor: 2.668