| Literature DB >> 19463690 |
Izabella Jastrzebska1, Leszek Siergiejczyk, Aneta M Tomkiel, Zofia Urbańczyk-Lipkowska, Dominik Wójcik, Jacek W Morzycki.
Abstract
The reaction of 23-oxotigogenin acetate with TMSOTf in THF afforded the corresponding bisnorcholanic lactone in 60% yield. The analogous reactions carried out in dichloromethane or benzene gave the rearranged products--the isomeric spirostanic ketone (10-15%) and bisfuran (40-42%). Similar products were also obtained upon treatment of 23,24-epoxysapogenins with BF(3). The epoxides treated with TiCl(4) afforded mostly chlorohydrins and no rearranged products were detected.Entities:
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Year: 2009 PMID： 19463690 DOI： 10.1016/j.steroids.2009.02.010
Source DB: PubMed Journal: Steroids ISSN： 0039-128X Impact factor: 2.668