Literature DB >> 19462241

New synthetic glucosyl-curcuminoids, and their (1)H and (13)C NMR characterization, from Curcuma longa L.

Monica Saladini1, Sandra Lazzari, Francesca Pignedoli, Roberto Rosa, Ferdinando Spagnolo, Erika Ferrari.   

Abstract

Turmeric extracts, among which curcumin and bis-demethoxycurcumin, are by far known for their therapeutic activities. In this study we propose easy and low cost synthetic pathways in order to obtain glucosyl-curcuminoids, safe and water soluble potential drugs and dyes, which may be implied in different fields ranging from pharmacology to food chemistry. The complete (1)H and (13)C NMR characterization of naturally occurring curcumin, bis-demethoxycurcumin and new synthetic glucosyl-curcuminoids is reported.

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Year:  2009        PMID： 19462241     DOI： 10.1007/s11130-009-0122-3

Source DB:  PubMed          Journal:  Plant Foods Hum Nutr        ISSN： 0921-9668            Impact factor:   3.921


  11 in total

1.  Antitumor agents. 250. Design and synthesis of new curcumin analogues as potential anti-prostate cancer agents.

Authors:  Li Lin; Qian Shi; Alexander K Nyarko; Kenneth F Bastow; Chin-Chung Wu; Ching-Yuan Su; Charles C-Y Shih; Kuo-Hsiung Lee
Journal:  J Med Chem       Date:  2006-06-29       Impact factor: 7.446

2.  Curcuminoids form reactive glucuronides in vitro.

Authors:  Erika Pfeiffer; Simone I Hoehle; Stephan G Walch; Alexander Riess; Anikó M Sólyom; Manfred Metzler
Journal:  J Agric Food Chem       Date:  2007-01-24       Impact factor: 5.279

3.  Changes in glycoprotein components in streptozotocin--nicotinamide induced type 2 diabetes: influence of tetrahydrocurcumin from Curcuma longa.

Authors:  Leelavinothan Pari; Pidaran Murugan
Journal:  Plant Foods Hum Nutr       Date:  2007-01-17       Impact factor: 3.921

4.  Anti-oxidant activities of curcumin and related enones.

Authors:  Waylon M Weber; Lucy A Hunsaker; Steve F Abcouwer; Lorraine M Deck; David L Vander Jagt
Journal:  Bioorg Med Chem       Date:  2005-06-01       Impact factor: 3.641

5.  A two generation reproductive toxicity study with curcumin, turmeric yellow, in Wistar rats.

Authors:  S Ganiger; H N Malleshappa; H Krishnappa; Geetha Rajashekhar; V Ramakrishna Rao; Frank Sullivan
Journal:  Food Chem Toxicol       Date:  2006-08-07       Impact factor: 6.023

6.  Phase I clinical trial of oral curcumin: biomarkers of systemic activity and compliance.

Authors:  Ricky A Sharma; Stephanie A Euden; Sharon L Platton; Darren N Cooke; Aisha Shafayat; Heather R Hewitt; Timothy H Marczylo; Bruno Morgan; David Hemingway; Simon M Plummer; Munir Pirmohamed; Andreas J Gescher; William P Steward
Journal:  Clin Cancer Res       Date:  2004-10-15       Impact factor: 12.531

7.  Studies on curcumin and curcuminoids XXXI. Symmetric and asymmetric curcuminoids: stability, activity and complexation with cyclodextrin.

Authors:  M A Tomren; M Másson; T Loftsson; H Hjorth Tønnesen
Journal:  Int J Pharm       Date:  2007-01-19       Impact factor: 5.875

8.  Novel curcumin analogs targeting TNF-induced NF-kappaB activation and proliferation in human leukemic KBM-5 cells.

Authors:  Ajit P Zambre; V M Kulkarni; Subhash Padhye; Santosh K Sandur; Bharat B Aggarwal
Journal:  Bioorg Med Chem       Date:  2006-07-14       Impact factor: 3.641

9.  Antioxidant and antimicrobial activity of Zingiberaceae plants in Taiwan.

Authors:  I-Nan Chen; Chen-Chin Chang; Chang-Chai Ng; Chung-Yi Wang; Yuan-Tay Shyu; Tsu-Liang Chang
Journal:  Plant Foods Hum Nutr       Date:  2007-12-20       Impact factor: 3.921

Review 10.  Curcumin: from ancient medicine to current clinical trials.

Authors:  H Hatcher; R Planalp; J Cho; F M Torti; S V Torti
Journal:  Cell Mol Life Sci       Date:  2008-06       Impact factor: 9.261
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