Literature DB >> 19462085

Using aptamers evolved from cell-SELEX to engineer a molecular delivery platform.

Prabodhika Mallikaratchy1, Haipeng Liu, Yu Fen Huang, Hui Wang, Dalia Lopez-Colon, Weihong Tan.   

Abstract

We report a chemically modified construct of the Sgc8 aptamer, selected against CEM cells, conjugated to an activator platform for stimulated release of molecules at the tumor surface using DNA template assisted functional group transfer reactions (DTGTR).

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Year:  2009        PMID: 19462085     DOI: 10.1039/b823258j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  6 in total

1.  Designing a bio-responsive robot from DNA origami.

Authors:  Eldad Ben-Ishay; Almogit Abu-Horowitz; Ido Bachelet
Journal:  J Vis Exp       Date:  2013-07-08       Impact factor: 1.355

2.  Cell-specific RNA aptamer against human CCR5 specifically targets HIV-1 susceptible cells and inhibits HIV-1 infectivity.

Authors:  Jiehua Zhou; Sangeetha Satheesan; Haitang Li; Marc S Weinberg; Kevin V Morris; John C Burnett; John J Rossi
Journal:  Chem Biol       Date:  2015-03-05

Review 3.  Nucleic acid aptamers: an emerging frontier in cancer therapy.

Authors:  Guizhi Zhu; Mao Ye; Michael J Donovan; Erqun Song; Zilong Zhao; Weihong Tan
Journal:  Chem Commun (Camb)       Date:  2012-11-04       Impact factor: 6.222

4.  Aptamer-labeled PLGA nanoparticles for targeting cancer cells.

Authors:  Athulya Aravind; Saino Hanna Varghese; Srivani Veeranarayanan; Anila Mathew; Yutaka Nagaoka; Seiki Iwai; Takahiro Fukuda; Takashi Hasumura; Yasuhiko Yoshida; Toru Maekawa; D Sakthi Kumar
Journal:  Cancer Nanotechnol       Date:  2012-01-19

5.  Aptamer-targeted DNA nanostructures with doxorubicin to treat protein tyrosine kinase 7-positive tumours.

Authors:  Mengting Liu; Wenjuan Ma; Qianshun Li; Dan Zhao; Xiaoru Shao; Qian Huang; Liying Hao; Yunfeng Lin
Journal:  Cell Prolif       Date:  2018-10-12       Impact factor: 6.831

Review 6.  Aptamers as therapeutics.

Authors:  Anthony D Keefe; Supriya Pai; Andrew Ellington
Journal:  Nat Rev Drug Discov       Date:  2010-07       Impact factor: 84.694

  6 in total

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