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Literature DB >> 19462078

Efficient copper-catalyzed coupling of aryl chlorides, bromides and iodides with aqueous ammonia.

Abstract

The copper(I)-catalyzed synthesis of a range of primary anilines from electron-rich and electron-deficient aryl halides including aryl chlorides has been achieved with aqueous ammonia, avoiding the need for inert atmosphere, expensive catalysts and ligands, anhydrous solvents, and additional base or other additives.

Entities: Chemical

Year: 2009 PMID： 19462078 DOI： 10.1039/b904188e

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

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Cited

6 in total

1. The Structure-Activity Relationship of a Tetrahydroisoquinoline Class of N-Methyl-d-Aspartate Receptor Modulators that Potentiates GluN2B-Containing N-Methyl-d-Aspartate Receptors.

Authors: Katie L Strong; Matthew P Epplin; John Bacsa; Christopher J Butch; Pieter B Burger; David S Menaldino; Stephen F Traynelis; Dennis C Liotta
Journal: J Med Chem Date: 2017-06-26 Impact factor: 7.446

2. Palladium-catalyzed coupling of ammonia with aryl chlorides, bromides, iodides, and sulfonates: a general method for the preparation of primary arylamines.

Authors: Giang D Vo; John F Hartwig
Journal: J Am Chem Soc Date: 2009-08-12 Impact factor: 15.419

6. New Stable Cu(I) Catalyst Supported on Weakly Acidic Polyacrylate Resin for Green C-N Coupling: Synthesis of N-(Pyridin-4-yl)benzene Amines and N,N-Bis(pyridine-4-yl)benzene Amines.

Authors: Nitin Kore; Pavel Pazdera
Journal: Molecules Date: 2016-12-22 Impact factor: 4.411

6 in total

Efficient copper-catalyzed coupling of aryl chlorides, bromides and iodides with aqueous ammonia.

1. The Structure-Activity Relationship of a Tetrahydroisoquinoline Class of N-Methyl-d-Aspartate Receptor Modulators that Potentiates GluN2B-Containing N-Methyl-d-Aspartate Receptors.

2. Palladium-catalyzed coupling of ammonia with aryl chlorides, bromides, iodides, and sulfonates: a general method for the preparation of primary arylamines.

3. Transitioning organic synthesis from organic solvents to water. What's your E Factor?

4. Tryptoline-based benzothiazoles re-sensitize MRSA to β-lactam antibiotics.

5. Design and synthesis of mycobacterial pks13 inhibitors: Conformationally rigid tetracyclic molecules.

6. New Stable Cu(I) Catalyst Supported on Weakly Acidic Polyacrylate Resin for Green C-N Coupling: Synthesis of N-(Pyridin-4-yl)benzene Amines and N,N-Bis(pyridine-4-yl)benzene Amines.