Literature DB >> 19462069

Synthesis of substituted pyridines and pyridazines via ring closing metathesis.

Timothy J Donohoe1, Lisa P Fishlock, José A Basutto, John F Bower, Panayiotis A Procopiou, Amber L Thompson.   

Abstract

RCM can be used to make aromatic heterocycles, namely pyridines and, for the first time, pyridazines; the key step after RCM involves elimination of sulfinate to provide the aromatic system.

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Year:  2009        PMID： 19462069     DOI： 10.1039/b904363b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

1.  Olefin cross-metathesis-based approaches to furans: procedures for the preparation of di- and trisubstituted variants.

Authors:  Timothy J Donohoe; John F Bower; José A Basutto
Journal:  Nat Protoc       Date:  2010-12-02       Impact factor: 13.491

2.  Three-component coupling sequence for the regiospecific synthesis of substituted pyridines.

Authors:  Ming Z Chen; Glenn C Micalizio
Journal:  J Am Chem Soc       Date:  2011-12-14       Impact factor: 15.419

3.  An expedient route to substituted furans via olefin cross-metathesis.

Authors:  Timothy J Donohoe; John F Bower
Journal:  Proc Natl Acad Sci U S A       Date:  2010-02-08       Impact factor: 11.205

4.  Quick construction of a C-N bond from arylsulfonyl hydrazides and Csp2-X compounds promoted by DMAP at room temperature.

Authors:  Kai Yang; Juan-Juan Gao; Shi-He Luo; Han-Qing Wu; Chu-Ming Pang; Bo-Wen Wang; Xiao-Yun Chen; Zhao-Yang Wang
Journal:  RSC Adv       Date:  2019-06-26       Impact factor: 3.361

5.  Total synthesis of the antitumor antibiotic (±)-streptonigrin: first- and second-generation routes for de novo pyridine formation using ring-closing metathesis.

Authors:  Timothy J Donohoe; Christopher R Jones; Anne F Kornahrens; Luiz C A Barbosa; Louise J Walport; Matthew R Tatton; Michael O'Hagan; Akshat H Rathi; David B Baker
Journal:  J Org Chem       Date:  2013-12-12       Impact factor: 4.354

6.  De novo synthesis of multisubstituted aryl amines using alkene cross metathesis.

Authors:  Matthew R Tatton; Iain Simpson; Timothy J Donohoe
Journal:  Org Lett       Date:  2014-03-19       Impact factor: 6.005
  6 in total

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