Rippled-pattern sebaceoma: a clinicopathological study.

We summarized the clinicopathological data of rippled-pattern sebaceoma diagnosed at Sapporo Institute for Dermatopathology and compared it with those of sebaceoma without rippled pattern. Eighty cases of sebaceoma, comprising 37 male and 43 female patients with a mean age at resection of 62.9 +/- 17.0 years, were reviewed. The lesions were located most frequently on the face (45.0%). Twenty-one (26.3%) of 80 cases of sebaceoma exhibited a rippled pattern. Rippled-pattern sebaceoma arose predominantly in males and most frequently on the scalp, whereas sebaceoma without rippled pattern occurred more frequently in females and on the face. Histopathologically, sebaceoma without rippled pattern frequently associated with other neoplastic lesions including sebaceous nevus, seborrheic keratosis, and trichoblastoma on the same lesion; however, there were no associated lesions in rippled-pattern sebaceoma.