Literature DB >> 19460336

Pushing single-gene genetic analysis up a Notch.

Ernst Hafen1.   

Abstract

Genetic screens in Drosophila have come a long way since the pioneering work of Nüsslein-Volhard and Wieschaus. A recent paper by Mummery-Widmer et al. illustrates the use of genome-wide RNAi-based reverse genetic screens in vivo and systems biology approaches to identify new components of the Notch signaling pathway.

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Year:  2009        PMID: 19460336     DOI: 10.1016/j.devcel.2009.05.006

Source DB:  PubMed          Journal:  Dev Cell        ISSN: 1534-5807            Impact factor:   12.270


  1 in total

1.  Vectors and parameters that enhance the efficacy of RNAi-mediated gene disruption in transgenic Drosophila.

Authors:  Benjamin Haley; Bryon Foys; Michael Levine
Journal:  Proc Natl Acad Sci U S A       Date:  2010-06-04       Impact factor: 11.205

  1 in total

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