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Literature DB >> 19460280

Carcinosarcomas (malignant mixed Müllerian tumor) of the uterus: advances in elucidation of biologic and clinical characteristics.

Abstract

Carcinosarcoma of the uterus (malignant mixed Müllerian tumor [MMMT]) is an uncommon, typically extremely aggressive neoplasm histologically composed of malignant epithelial and mesenchymal (stromal) elements. Although the literature contains some debate, most authors now agree that most MMMTs derive from sarcomatous differentiation in a high-grade carcinoma. This article reviews the clinical and histopathologic features of this interesting neoplasm, with particular emphasis on recent data supporting MMMTs as primarily epithelial malignant neoplasms with areas of mesenchymal/spindle cell differentiation.

Entities: Disease

Mesh：

Year: 2009 PMID： 19460280 DOI： 10.6004/jnccn.2009.0037

Source DB: PubMed Journal: J Natl Compr Canc Netw ISSN： 1540-1405 Impact factor: 11.908

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Cited

29 in total

1. Assessing inter-component heterogeneity of biphasic uterine carcinosarcomas.

Authors: Yihua Liu; Zachary Weber; F Anthony San Lucas; Aditya Deshpande; Yasminka A Jakubek; Raed Sulaiman; Mary Fagerness; Natasha Flier; Joseph Sulaiman; Christel M Davis; Jerry Fowler; David Starks; Luis Rojas-Espaillat; Alexander J Lazar; Gareth E Davies; Erik A Ehli; Paul Scheet
Journal: Gynecol Oncol Date: 2018-09-05 Impact factor: 5.482

Review 2. Gynecologic biopsy for molecular profiling: a review for the interventional radiologist.

Authors: Bradley R Corr; Kian Behbakht; Monique A Spillman
Journal: Semin Intervent Radiol Date: 2013-12 Impact factor: 1.513

3. Impact of adjuvant therapy on recurrence patterns in stage I uterine carcinosarcoma.

Authors: Koji Matsuo; Kohei Omatsu; Malcolm S Ross; Marian S Johnson; Mayu Yunokawa; Merieme M Klobocista; Dwight D Im; Stephen H Bush; Yutaka Ueda; Tadao Takano; Erin A Blake; Kosei Hasegawa; Tsukasa Baba; Masako Shida; Shinya Satoh; Takuhei Yokoyama; Hiroko Machida; Sosuke Adachi; Yuji Ikeda; Keita Iwasaki; Takahito M Miyake; Shiori Yanai; Masato Nishimura; Tadayoshi Nagano; Munetaka Takekuma; Satoshi Takeuchi; Tanja Pejovic; Mian Mk Shahzad; Frederick R Ueland; Joseph L Kelley; Lynda D Roman
Journal: Gynecol Oncol Date: 2017-02-16 Impact factor: 5.482

4. Mutational landscape implicates epithelial-mesenchymal transition gene TGF-β2 mutations for uterine carcinosarcoma after adjuvant tamoxifen therapy for breast carcinoma.

Authors: Ling Shen; Liangli Hong; Songxia Zhou; Guohong Zhang; Ruiqin Mai
Journal: Int J Clin Exp Pathol Date: 2019-03-01

5. Gallbladder carcinosarcoma.

Authors: Jeffrey J Pu; Weize Wu
Journal: BMJ Case Rep Date: 2011-04-01

6. Solitary splenic metastasis from ovarian carcinosarcoma: a case report.

Authors: Alex B Olsen; Sabine Pargman; Thomas Gillespie
Journal: J Med Case Rep Date: 2011-02-10

7. Predictive and Prognostic Factors in Ovarian and Uterine Carcinosarcomas.

Authors: İrfan Cicin; Tahsin Özatlı; Esma Türkmen; Türkan Özturk; Melike Özçelik; Devrim Çabuk; Ayşe Gökdurnalı; Özlem Balvan; Yaşar Yıldız; Metin Şeker; Nuriye Özdemir; Burcu Yapar; Özgür Tanrıverdi; Yusuf Günaydin; Serkan Menekşe; Berna Öksüzoğlu; Asude Aksoy; Bülent Erdogan; M Bekir Hacıoglu; Erkan Arpaci; Alper Sevinç
Journal: Balkan Med J Date: 2016-09-01 Impact factor: 2.021