Literature DB >> 19459860

Sterile water injection for labour pain: a systematic review and meta-analysis of randomised controlled trials.

E K Hutton1, M Kasperink, M Rutten, A Reitsma, B Wainman.   

Abstract

BACKGROUND: Up to one-third of labouring women will experience painful 'back labour'. Sterile water injected lateral to the lumbosacral spine is a simple and well-researched approach to this pain.
OBJECTIVE: To determine if sterile water injection for low back pain compared to placebo or alternative therapy increased or decreased the rate of Caesarean section. SEARCH STRATEGY: We performed a literature search with no language restriction in four databases: the Cochrane library, EMBASE (1980-2009), Ovid Medline (1950-2009) and CINAHL (1982-2009). SELECTION CRITERIA: We included all randomised controlled trials (RCTs) of sterile water injection for labour pain that included outcomes of interest and original data. DATA COLLECTION AND ANALYSIS: We compared Caesarean section rates among women who received sterile water injection in labour with those who received either placebo treatment or another non-pharmacological treatment modality. Other outcomes included pain scores, use of regional analgesia and women's assessment of treatment. We used Revman 5 for the meta-analysis. Data were entered by one reviewer and independently cross-checked. Pooled outcomes were reported as Relative Risk (RR) or Weighted Mean Difference using Mantel-Haenszel fixed-effects model except when the I2 value >50% indicated significant heterogeneity in which case random-effects model was used. MAIN
RESULTS: We included eight RCTs. The Caesarean section rate was 4.6% in the sterile water injection group and 9.9% in the comparison group (n = 828) (RR 0.51, 95% CI: 0.30, 0.87).
CONCLUSION: We believe that a large RCT should be mounted to validate our findings regarding the impact of sterile water injections on mode of delivery.

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Year:  2009        PMID: 19459860     DOI: 10.1111/j.1471-0528.2009.02221.x

Source DB:  PubMed          Journal:  BJOG        ISSN: 1470-0328            Impact factor:   6.531


  12 in total

Review 1.  New Labor Pain Treatment Options.

Authors:  Veerandra Koyyalamudi; Gurleen Sidhu; Elyse M Cornett; Viet Nguyen; Carmen Labrie-Brown; Charles J Fox; Alan D Kaye
Journal:  Curr Pain Headache Rep       Date:  2016-02

2.  Intracutaneous sterile water injection for pain relief during extracorporeal shock wave lithotripsy: comparison with diclofenac sodium.

Authors:  Abdullah Gul; Murat Gul
Journal:  Urolithiasis       Date:  2019-07-05       Impact factor: 3.436

3.  Comparative Analgesic Effects of Intradermal and Subdermal Injection of Sterile Water on Active Labor Pain.

Authors:  Fariba Almassinokiani; Nasim Ahani; Peyman Akbari; Poupak Rahimzadeh; Hossein Akbari; Fatemeh Sharifzadeh
Journal:  Anesth Pain Med       Date:  2020-04-25

4.  Caesarean delivery rates and analgesia effectiveness following injections of sterile water for back pain in labour: A multicentre, randomised placebo controlled trial.

Authors:  Nigel Lee; Yu Gao; Sally L Collins; Lena B Mårtensson; Wendy Randall; Toni-Marie Rowe; Sue Kildea
Journal:  EClinicalMedicine       Date:  2020-07-03

Review 5.  Pain management for women in labour: an overview of systematic reviews.

Authors:  Leanne Jones; Mohammad Othman; Therese Dowswell; Zarko Alfirevic; Simon Gates; Mary Newburn; Susan Jordan; Tina Lavender; James P Neilson
Journal:  Cochrane Database Syst Rev       Date:  2012-03-14

6.  A randomised non-inferiority controlled trial of a single versus a four intradermal sterile water injection technique for relief of continuous lower back pain during labour.

Authors:  Nigel Lee; Peter Coxeter; Michael Beckmann; Joan Webster; Vanessa Wright; Tric Smith; Sue Kildea
Journal:  BMC Pregnancy Childbirth       Date:  2011-03-23       Impact factor: 3.007

7.  The Effect of Subcutaneous and Intracutaneous Injections of Sterile Water and Normal Saline on Pain Intensity in Nulliparous Women: A Randomized Controlled Trial.

Authors:  Mehri Rezaie; Sanaz Shaabani; Farzin Sabouri Jahromi; Maryam Efafat Jahromi; Sheida Dakhesh
Journal:  Iran J Nurs Midwifery Res       Date:  2019 Sep-Oct

8.  Labour analgesia in cardiac parturients: A personalised approach!

Authors:  Nitin Choudhary; Kirti Nath Saxena; Bharti Wadhwa; Rohan Magoon
Journal:  Indian J Anaesth       Date:  2020-11-01

9.  Impact on caesarean section rates following injections of sterile water (ICARIS): a multicentre randomised controlled trial.

Authors:  Nigel Lee; Lena B Mårtensson; Caroline Homer; Joan Webster; Kristen Gibbons; Helen Stapleton; Natalie Dos Santos; Michael Beckmann; Yu Gao; Sue Kildea
Journal:  BMC Pregnancy Childbirth       Date:  2013-05-03       Impact factor: 3.007

10.  Dutch women in midwife-led care at the onset of labour: which pain relief do they prefer and what do they use?

Authors:  Trudy Klomp; Ank de Jonge; Eileen K Hutton; Antoine L M Lagro-Janssen
Journal:  BMC Pregnancy Childbirth       Date:  2013-12-10       Impact factor: 3.007

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