Michael Berk1. 1. Melbourne University, Barwon Health and the Geelong Clinic, Mental Health Research Institute, and Orygen Research Centre, Victoria. mikebe@barwonhealth.org.au
Abstract
BACKGROUND: Sleep disorders are particularly common in the primary care setting, and are intimately interlinked with depression. OBJECTIVE: This article aims to review the relationship between sleep and depression, with an emphasis on the foundation and clinical salience of this relationship. DISCUSSION: Depression is the most common cause of insomnia, and insomnia is highly prevalent in depression. This association has a well characterised physiological foundation. Sleep disorder in depression has prognostic and therapeutic implications. Residual insomnia after remission of depression is predictive of relapse, and prominent insomnia predicts a poorer treatment outcome in depression. Evidence based management involves integrating both pharmacological and behavioural strategies; the latter includes sleep hygiene and regulating diurnal rhythms.
BACKGROUND:Sleep disorders are particularly common in the primary care setting, and are intimately interlinked with depression. OBJECTIVE: This article aims to review the relationship between sleep and depression, with an emphasis on the foundation and clinical salience of this relationship. DISCUSSION: Depression is the most common cause of insomnia, and insomnia is highly prevalent in depression. This association has a well characterised physiological foundation. Sleep disorder in depression has prognostic and therapeutic implications. Residual insomnia after remission of depression is predictive of relapse, and prominent insomnia predicts a poorer treatment outcome in depression. Evidence based management involves integrating both pharmacological and behavioural strategies; the latter includes sleep hygiene and regulating diurnal rhythms.
Authors: Lauren Clevenger; Andrew Schrepf; Koenraad Degeest; David Bender; Michael Goodheart; Amina Ahmed; Laila Dahmoush; Frank Penedo; Joseph Lucci; Premal H Thaker; Luis Mendez; Anil K Sood; George M Slavich; Susan K Lutgendorf Journal: Cancer Date: 2013-06-24 Impact factor: 6.860
Authors: Paul Campbell; Nicole Tang; John McBeth; Martyn Lewis; Chris J Main; Peter R Croft; Hannah Morphy; Kate M Dunn Journal: Sleep Date: 2013-11-01 Impact factor: 5.849