Literature DB >> 1945823

Bleeding in acute promyelocytic leukemia (APL): fibrinolysis or defibrination?

I Krsnik1, A Escribá, M López-Rubio, C Alarcón, E del Potro, J Díaz-Mediavilla.   

Abstract

The coagulation abnormalities in 20 cases of acute promyelocytic leukemia (APL) treated at a single institution were reviewed. A remarkably uniform picture of defibrination and increased FDPs with well-preserved levels of other coagulation factors including AT-III was seen. Our data, together with those available in the literature, do not support DIC as the underlying mechanism of bleeding but seem rather to point to increased proteolysis as the cause.

Entities:  

Mesh:

Substances:

Year:  1991        PMID: 1945823

Source DB:  PubMed          Journal:  Nouv Rev Fr Hematol


  1 in total

1.  Long-term follow-up results of cytarabine-containing chemotherapy for acute promyelocytic leukemia.

Authors:  Young Hoon Park; Dae-Young Kim; Yeung-Chul Mun; Eun Kyung Cho; Jae Hoon Lee; Deog-Yeon Jo; Inho Kim; Sung-Soo Yoon; Seon Yang Park; Byoungkook Kim; Soo-Mee Bang; Hawk Kim; Young Joo Min; Jae Hoo Park; Jong Jin Seo; Hyung Nam Moon; Moon Hee Lee; Chul Soo Kim; Won Sik Lee; So Young Chong; Doyeun Oh; Dae Young Zang; Kyung Hee Lee; Myung Soo Hyun; Heung Sik Kim; Sung-Hyun Kim; Hyukchan Kwon; Hyo Jin Kim; Kyung Tae Park; Sung Hwa Bae; Hun Mo Ryoo; Jung Hye Choi; Myung-Ju Ahn; Hwi-Joong Yoon; Sung-Hyun Nam; Bong-Seog Kim; Chu-Myong Seong
Journal:  Korean J Intern Med       Date:  2022-06-28       Impact factor: 3.165

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.