Literature DB >> 19457304

[Update of the topical treatment of psoriasis].

J M Carrascosa1, F Vanaclocha, L Borrego, E Fernández-López, A Fuertes, L Rodríguez-Fernández-Freire, A Zulaica, A Tuneu, G Caballé, E Colomé, X Bordas, J M Hernanz, C Brufau, E Herrera.   

Abstract

Topical therapy continues to be one of the pillars of psoriasis management. Topical corticosteroids and vitamin D analogs are the drugs of choice during the induction phase, and vitamin D analogs continue to be drugs of choice for maintenance therapy. Tazarotene and dithranol are suitable options in patients with certain, specific characteristics. The calcineurin inhibitors can be considered to be second-line treatment for psoriasis of the face and flexures. The efficacy and safety of the fixed-dose combination of betamethasone and calcipotriol in the induction phase is greater than that of either drug alone. The combination of corticosteroids with salicylic acid achieves better results than corticosteroids in monotherapy. None of the drugs evaluated stands out over the others in all clinical situations, and their use must therefore be individualized in each patient and adjusted according to the course of the disease.

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Year:  2009        PMID: 19457304

Source DB:  PubMed          Journal:  Actas Dermosifiliogr        ISSN: 0001-7310


  5 in total

1.  Calcipotriol delivery into the skin as emulgel for effective permeation.

Authors:  V Naga Sravan Kumar Varma; P V Maheshwari; M Navya; Sharath Chandra Reddy; H G Shivakumar; D V Gowda
Journal:  Saudi Pharm J       Date:  2014-02-25       Impact factor: 4.330

2.  Associations Between Non-neurological Autoimmune Disorders and Psychosis: A Meta-analysis.

Authors:  Alexis E Cullen; Scarlett Holmes; Thomas A Pollak; Graham Blackman; Dan W Joyce; Matthew J Kempton; Robin M Murray; Philip McGuire; Valeria Mondelli
Journal:  Biol Psychiatry       Date:  2018-06-28       Impact factor: 13.382

3.  A PAMPA assay as fast predictive model of passive human skin permeability of new synthesized corticosteroid C-21 esters.

Authors:  Bojan D Markovic; Sote M Vladimirov; Olivera A Cudina; Jadranka V Odovic; Katarina D Karljikovic-Rajic
Journal:  Molecules       Date:  2012-01-05       Impact factor: 4.411

4.  Efficacy of nano-modified Runji ointment in the treatment of mild and moderate psoriasis with blood dryness syndrome: a study protocol for a double-blind randomized controlled trial.

Authors:  Guanru Li; Liyun Sun; Yue Qiu; Yaquan Hou; Libo Du; Kaixuan Zhao; Jiali Qian; Jiuli Liu; Tengfei Ma
Journal:  Medicine (Baltimore)       Date:  2021-12-30       Impact factor: 1.889

Review 5.  Calcipotriol/betamethasone for the treatment of psoriasis: efficacy, safety, and patient acceptability.

Authors:  Christina Rogalski
Journal:  Psoriasis (Auckl)       Date:  2015-06-08
  5 in total

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