Literature DB >> 19456288

Second-generation histamine H(2)-receptor antagonists with gastric mucosal defensive properties.

Takafumi Ichikawa1, Kyoko Hotta, Kazuhiko Ishihara.   

Abstract

Unlike the earlier agents in this class, certain of the newer histamine H(2)-receptor antagonists (so-called second-generation HB(2B)-receptor antagonists) have recently been reported to promote gastric mucosal defenses. We review herein the structure, specificity, and mechanisms of these agents with a special focus on their cytoprotective/gastroprotective actions.

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Year:  2009        PMID： 19456288     DOI： 10.2174/138955709788167646

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  6 in total

1.  Effect of lansoprazole versus roxatidine on prevention of bleeding and promotion of ulcer healing after endoscopic submucosal dissection for superficial gastric neoplasia.

Authors:  Hiroyuki Imaeda; Naoki Hosoe; Hidekazu Suzuki; Yoshimasa Saito; Yosuke Ida; Rieko Nakamura; Yasushi Iwao; Haruhiko Ogata; Toshifumi Hibi
Journal:  J Gastroenterol       Date:  2011-07-30       Impact factor: 7.527

2.  Changes in the mucus barrier during cisplatin-induced intestinal mucositis in rats.

Authors:  Hajime Yamamoto; Kazuhiko Ishihara; Yuko Takeda; Wasaburo Koizumi; Takafumi Ichikawa
Journal:  Biomed Res Int       Date:  2013-12-23       Impact factor: 3.411

3.  Cytoprotective gastric pentadecapeptide BPC 157 resolves major vessel occlusion disturbances, ischemia-reperfusion injury following Pringle maneuver, and Budd-Chiari syndrome.

Authors:  Predrag Sikiric; Anita Skrtic; Slaven Gojkovic; Ivan Krezic; Helena Zizek; Eva Lovric; Suncana Sikiric; Mario Knezevic; Sanja Strbe; Marija Milavic; Antonio Kokot; Alenka Boban Blagaic; Sven Seiwerth
Journal:  World J Gastroenterol       Date:  2022-01-07       Impact factor: 5.742

4.  Cimetidine-Based Cationic Amphiphiles for In Vitro Gene Delivery Targetable to Colon Cancer.

Authors:  Shireesha Manturthi; Dwaipayan Bhattacharya; Kalyani Rajesh Sakhare; Kumar Pranav Narayan; Srilakshmi V Patri
Journal:  ACS Omega       Date:  2022-08-25

5.  Crocin exerts improving effects on indomethacin-induced small intestinal ulcer by antioxidant, anti-inflammatory and anti-apoptotic mechanisms.

Authors:  Sadat Ghafarzadeh; Rahim Hobbenaghi; Esmaeal Tamaddonfard; Amir Abbas Farshid; Mehdi Imani
Journal:  Vet Res Forum       Date:  2019-12-15       Impact factor: 1.054

6.  Histamine H2-Receptor Antagonists Improve Non-Steroidal Anti-Inflammatory Drug-Induced Intestinal Dysbiosis.

Authors:  Rei Kawashima; Shun Tamaki; Fumitaka Kawakami; Tatsunori Maekawa; Takafumi Ichikawa
Journal:  Int J Mol Sci       Date:  2020-10-31       Impact factor: 5.923
  6 in total

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