Literature DB >> 19454933

Orbital wall fracture repair using Seprafilm.

Mehryar Taban1, Tanuj Nakra, Ronald Mancini, Raymond S Douglas, Robert A Goldberg.   

Abstract

PURPOSE: Seprafilm is a hybrid product of carboxymethylcellulose and sodium hyaluronate that can act as an absorbable barrier to decrease the formation and severity of postoperative adhesions in abdominal, thoracic, and pelvic surgeries. The authors report their experience with use of Seprafilm in "trap door" orbital wall fracture repair.
METHODS: Retrospective case series of 4 consecutive patients with trap door orbital wall fractures secondary to blunt trauma with entrapped orbital soft tissue who underwent surgical repair with placement of Seprafilm implant in 2008. Orbitotomy was performed via standard transconjunctival and/or transcaruncular approaches with release of entrapped tissues, and placement of Seprafilm implant over the fracture site without fixation. Patients were followed for at least 6 months. Ophthalmic and orbital examinations, including ocular motility and Hertel exophthalmometry measurements, were recorded.
RESULTS: All 6 orbital wall fractures (4 floor, 2 medial wall) were successfully corrected with resolution of restrictive motility in the follow-up period (average 10 months; range 6 months to 1.5 years). Mean patient age was 13.5 years (range, 9-20 years). Two of the 4 patients had 2 separate fractures. There were no complications and no need for reoperation.
CONCLUSIONS: Seprafilm may have a role in reconstruction of the "trap door" type of orbital wall fractures. The ease of use, lack of fixation, and absorbable properties without inflammation are encouraging for further study.

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Year:  2009        PMID: 19454933     DOI: 10.1097/IOP.0b013e3181a2fd1e

Source DB:  PubMed          Journal:  Ophthalmic Plast Reconstr Surg        ISSN: 0740-9303            Impact factor:   1.746


  4 in total

1.  Adhesiotomy with grafting of fat and perifascial areolar tissue for adhesions of extraocular muscles after trauma or surgery.

Authors:  Taro Kamisasanuki; Nobutada Katori; Kenichiro Kasai; Kengo Hayashi; Kenichi Kokubo; Yu Ota; Taiji Sakamoto
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2014-03-28       Impact factor: 3.117

2.  Clinical effect of a mixed solution of sodium hyaluronate and sodium carboxymethylcellulose during the transconjunctival approach for orbital wall reconstruction.

Authors:  Byung Wan Kang; Hyo Seok Lee; Han Jin Oh; Kyung Chul Yoon
Journal:  Chonnam Med J       Date:  2012-08-24

3.  Efficacy of Seprafilm(®) graft with adhesiolysis in experimentally induced lid adhesion in rabbits.

Authors:  Sang Wook Jin; Hee Bae Ahn; Mi Sook Roh; Yoon Hyung Kwon; Won Yeol Ryu
Journal:  Int J Ophthalmol       Date:  2013-02-18       Impact factor: 1.779

4.  Seprafilm® adhesion barrier: (1) a review of preclinical, animal, and human investigational studies.

Authors:  Michael P Diamond; Ellen L Burns; Beverly Accomando; Sadiqa Mian; Lena Holmdahl
Journal:  Gynecol Surg       Date:  2012-04-20
  4 in total

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