Literature DB >> 19454899

Association between prehypertension and clustering of cardiovascular disease risk factors among Chinese adults.

Dahai Yu1, Jianfeng Huang, Dongsheng Hu, Jichun Chen, Jie Cao, Jianxin Li, Dongfeng Gu.   

Abstract

PURPOSE: We aimed to estimate the association between prehypertension (PHT) and clustering of cardiovascular disease (CVD) risk factors among Chinese adults.
METHODS: A cross-sectional survey in a nationally representative sample of 15,540 Chinese adults aged 35-74 years was conducted during 2000-2001.
RESULTS: Overall, 79.4%, 40.0%, and 11.0% of Chinese adults with PHT (120-139/80-89 mm Hg) had >or=1, >or=2, and >or=3 modifiable CVD risk factors (dyslipidemia, impaired fasting glucose/diabetes, cigarette smoking, and overweight/obesity), respectively. The adjusted odds ratio (95% confidence interval, CI) of having >or=1, >or=2, and >or=3 CVD risk factors was 1.41 (1.24-1.61), 1.45 (1.30-1.61), and 1.96 (1.67-2.29), respectively, for adults with PHT compared with those with optimal blood pressure by multivariate models. Moreover, population attributable risk percent of having >or=1, >or=2, and >or=3 CVD risk factors was 16.7%, 18.0%, and 31.9%, respectively, for adults with PHT. Furthermore, among adults with PHT, higher prevalence, adjusted odds ratios, and population attributable risk percent of having >or=1, >or=2, and >or=3 CVD risk factors were more likely to be found among people with high normal blood pressure (130-139/85-89 mm Hg) compared with their counterparts with normal blood pressure (120-129/80-84 mm Hg).
CONCLUSIONS: Clustering of CVD risk factors is common among Chinese adults with PHT, especially with high normal blood pressure. Global lifestyle modification would be a very important nonpharmaceutical therapy to reduce the increasing burden of CVD in China.

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Year:  2009        PMID: 19454899     DOI: 10.1097/FJC.0b013e3181a02238

Source DB:  PubMed          Journal:  J Cardiovasc Pharmacol        ISSN: 0160-2446            Impact factor:   3.105


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