Literature DB >> 19453918

Post-radical prostatectomy pharmacological penile rehabilitation: practice patterns among the international society for sexual medicine practitioners.

Patrick Teloken1, Guilherme Mesquita, Francesco Montorsi, John Mulhall.   

Abstract

INTRODUCTION: Despite the fact that there is minimal evidence-based data supporting it, the concept of pharmacological penile rehabilitation following radical prostatectomy (RP) is receiving great attention. AIM: To define attitudes and practice patterns of clinicians who were members of the International Society for Sexual Medicine (ISSM) and/or its affiliated societies.
METHODS: Members of the ISSM and its regional affiliates were invited to participate in a web-based survey. MAIN OUTCOME MEASURES: Demographic factors, current practice status, and opinions regarding post-RP erectile dysfunction and penile rehabilitation. The statistical methods used included chi-square, Student's t-tests, and logistic regression analysis.
RESULTS: Three hundred-one physicians from 41 countries completed the questionnaire (82% were urologists). Sixty-five percent of the responders had formal sexual medicine specialty training, 44% had uro-oncology specialty training, and 60% performed RPs. Eighty-seven percent performed some form of rehabilitation. As part of the primary rehabilitation strategy, 95% used phosphodiesterase type 5 inhibitors (PDE5), 30% used vacuum device, 75% used intracavernosal injections, and 9.9% used intraurethral prostaglandin. Fifty-four percent commenced rehabilitation immediately/just after urethral catheter removal, and 37% within the first 4 months after RP. Neither the number of years in medical practice, clinician age, nor country/region of practice differed between rehabilitation performers and non-performers. With regard to the primary reason for avoiding rehabilitation: 50% responded said it is the cost; 25% said the fact that it is not evidence-based; and 25% said they were not familiar with the concept. Performing rehabilitation was positively associated with urologic oncology training (P = 0.03), performing RP (P < 0.001), and seeing over 50 post-RP patients per year (P = 0.011).
CONCLUSIONS: Among ISSM members post-RP penile rehabilitation is widely practiced, commenced early, and based predominantly on PDE5 inhibitors and intracavernosal injections. Clinicians who perform RP or see over 50 such patients per year are the most likely to perform rehabilitation. Cost represents the most common reason for rehabilitation neglect.

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Year:  2009        PMID: 19453918     DOI: 10.1111/j.1743-6109.2009.01269.x

Source DB:  PubMed          Journal:  J Sex Med        ISSN: 1743-6095            Impact factor:   3.802


  31 in total

1.  Postprostatectomy erectile dysfunction: the role of penile rehabilitation.

Authors:  Brian P Defade; Culley C Carson; Michael J Kennelly
Journal:  Rev Urol       Date:  2011

2.  Are We Improving Erectile Function Recovery After Radical Prostatectomy? Analysis of Patients Treated over the Last Decade.

Authors:  Paolo Capogrosso; Emily A Vertosick; Nicole E Benfante; James A Eastham; Peter J Scardino; Andrew J Vickers; John P Mulhall
Journal:  Eur Urol       Date:  2018-09-17       Impact factor: 20.096

3.  Erectogenic and neurotrophic effects of icariin, a purified extract of horny goat weed (Epimedium spp.) in vitro and in vivo.

Authors:  Alan W Shindel; Zhong-Chen Xin; Guiting Lin; Thomas M Fandel; Yun-Ching Huang; Lia Banie; Benjamin N Breyer; Maurice M Garcia; Ching-Shwun Lin; Tom F Lue
Journal:  J Sex Med       Date:  2010-02-05       Impact factor: 3.802

Review 4.  Erectile dysfunction after radical prostatectomy: treatment options.

Authors:  Sidney Glina
Journal:  Drugs Aging       Date:  2011-04-01       Impact factor: 3.923

5.  Words of wisdom. Re: Effect of nightly versus on-demand vardenafil on recovery of erectile function in men following bilateral nerve-sparing radical prostatectomy.

Authors:  Alan W Shindel; Tom F Lue
Journal:  Eur Urol       Date:  2009-12       Impact factor: 20.096

6.  The Prostate Cancer Rehabilitation Clinic: a biopsychosocial clinic for sexual dysfunction after radical prostatectomy.

Authors:  A Matthew; N Lutzky-Cohen; L Jamnicky; K Currie; A Gentile; D Santa Mina; N Fleshner; A Finelli; R Hamilton; G Kulkarni; M Jewett; A Zlotta; J Trachtenberg; Z Yang; D Elterman
Journal:  Curr Oncol       Date:  2018-12-01       Impact factor: 3.677

7.  Comparison of the efficacy and safety of 5-mg once-daily versus 5-mg alternate-day tadalafil in men with erectile dysfunction and lower urinary tract symptoms.

Authors:  H Choi; J-H Kim; J-S Shim; J Y Park; S H Kang; D G Moon; J Cheon; J G Lee; J J Kim; J-H Bae
Journal:  Int J Impot Res       Date:  2014-07-03       Impact factor: 2.896

Review 8.  Erection rehabilitation following prostatectomy--current strategies and future directions.

Authors:  Nikolai A Sopko; Arthur L Burnett
Journal:  Nat Rev Urol       Date:  2016-03-15       Impact factor: 14.432

9.  Penile Rehabilitation Strategies Among Prostate Cancer Survivors.

Authors:  Fouad Aoun; Alexandre Peltier; Roland van Velthoven
Journal:  Rev Urol       Date:  2015

10.  Efficacy of vacuum erectile devices (VEDs) after radical prostatectomy: the initial Irish experience of a dedicated VED clinic.

Authors:  G J Nason; F McNamara; M Twyford; F O'Kelly; S White; E Dunne; G C Durkan; S K Giri; G P Smyth; R E Power
Journal:  Int J Impot Res       Date:  2016-05-26       Impact factor: 2.896

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