Ming Jin Lim1, Jean-Pierre Lin. 1. Paediatric Neurology Department, Evelina Children's Hospital, Guy's and St Thomas' Hospitals NHS Foundation Trust, Lambeth Palace Road, London, SE1 7EH, UK. Ming.lim@gstt.nhs.uk
Abstract
PURPOSE: The effects of pCO2 on cerebral spinal fluid (CSF) pressure measurement were observed in four patients. METHODS: Children presenting with either a diagnosis or suspected diagnosis of IIH, who were undergoing lumbar puncture under a general anaesthetic for pressure measurement, were recruited to study the relationship between pCO2 and CSF pressure measurements. RESULTS: A rise of end-tidal pCO2 by 1 kPa causes a rise of CSF pressure by 3.5-12 cm H20. CONCLUSION: Controlling of pCO2 is important when measuring CSF pressure to prevent misdiagnosis and over treatment of patients with idiopathic intracranial hypertension (IIH).
PURPOSE: The effects of pCO2 on cerebral spinal fluid (CSF) pressure measurement were observed in four patients. METHODS:Children presenting with either a diagnosis or suspected diagnosis of IIH, who were undergoing lumbar puncture under a general anaesthetic for pressure measurement, were recruited to study the relationship between pCO2 and CSF pressure measurements. RESULTS: A rise of end-tidal pCO2 by 1 kPa causes a rise of CSF pressure by 3.5-12 cm H20. CONCLUSION: Controlling of pCO2 is important when measuring CSF pressure to prevent misdiagnosis and over treatment of patients with idiopathic intracranial hypertension (IIH).
Authors: Clare L Fraser; Donald L Bliwise; Nancy J Newman; Cédric Lamirel; Nancy A Collop; David B Rye; Lynn Marie Trotti; Valérie Biousse; Beau B Bruce Journal: J Neuroophthalmol Date: 2013-09 Impact factor: 3.042
Authors: Samson Gwer; Victoria Sheward; Anthony Birch; Robert Marchbanks; Richard Idro; Charles R Newton; Fenella J Kirkham; Jean-Pierre Lin; Ming Lim Journal: Childs Nerv Syst Date: 2013-01-30 Impact factor: 1.475