Literature DB >> 19451702

The usefulness of inspiratory flow rate during inhalation corticosteroid therapy in asthma.

Masashi Banno1, Hidenori Ibata, Takashi Niimi, Shigeki Sato, Ryo Matsushita.   

Abstract

BACKGROUND: The recently released handheld In-Check device can be used to measure the peak inspiratory flow rate (PIF) of patients and is reportedly useful in determining whether the PIF is sufficient for using inhaler devices. In this study, we evaluated the effects of instructions for the use of the device and of the device type based on measurements of the PIF in asthma.
OBJECTIVES: One hundred and thirty-five asthmatic patients who used a fluticasone propionate Diskus (FP-DK) or a budesonide Turbuhaler (BUD-TH) were studied.
METHODS: The PIF was measured by the In-Check device. For patients without a sufficient PIF of 50 l/min, instructions for the use of the device were given, and the device was changed to hydrofluoroalkan-beclomethasone dipropionate (HFA-BDP).
RESULTS: A significant correlation between the PIF and peak expiratory flow rate (p < 0.0001) was found. In 10 patients in whom the PIF did not increase to >50 l/min after instructions, the device was changed to HFA-BDP, which resulted in significant improvements in lung function in terms of the forced expiratory volume in 1 s (p = 0.018), peak expiratory flow (p = 0.038) and the maximum expiratory flow rates at 50% (p = 0.018) and 25% (p = 0.011).
CONCLUSIONS: Measurement of the PIF by the In-Check device is useful in the clinical management of asthma, to provide an appropriate device so as to improve lung function.
Copyright © 2009 S. Karger AG, Basel.

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Year:  2009        PMID: 19451702     DOI: 10.1159/000220097

Source DB:  PubMed          Journal:  Respiration        ISSN: 0025-7931            Impact factor:   3.580


  2 in total

1.  Prevalence of Low Peak Inspiratory Flow Rate at Discharge in Patients Hospitalized for COPD Exacerbation.

Authors:  Gulshan Sharma; Donald A Mahler; Valerie M Mayorga; Kathleen L Deering; Oing Harshaw; Vaidyanathan Ganapathy
Journal:  Chronic Obstr Pulm Dis       Date:  2017-07-15

2.  Maximal inspiratory and expiratory flow at moderate altitude: a study of a Latin American population.

Authors:  Laura Gochicoa-Rangel; Keylin Yaoska Rodríguez-Peralta; Ana Karen Gutiérrez-Bautista; Carlos Guzmán-Valderrábano; Rosario Fernández-Plata; Luis Torre-Bouscoulet; David Martínez-Briseño
Journal:  BMC Pulm Med       Date:  2022-04-19       Impact factor: 3.320

  2 in total

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