Literature DB >> 19451296

Analysis of single-nucleotide polymorphisms in the crt-o and mdr1 genes of Plasmodium vivax among chloroquine-resistant isolates from the Brazilian Amazon region.

Pamela Orjuela-Sánchez1, Franklin Simões de Santana Filho, Ariane Machado-Lima, Yonne Francis Chehuan, Mônica Regina Farias Costa, Maria das Graças Costa Alecrim, Hernando A del Portillo.   

Abstract

Plasmodium vivax parasites with chloroquine resistance (CQR) are already circulating in the Brazilian Amazon. Complete single-nucleotide polymorphism (SNP) analyses of coding and noncoding sequences of the pvmdr1 and pvcrt-o genes revealed no associations with CQR, even if some mutations had not been randomly selected. In addition, striking differences in the topologies and numbers of SNPs in these transporter genes between P. vivax and P. falciparum reinforce the idea that mechanisms other than mutations may explain this virulent phenotype in P. vivax.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19451296      PMCID： PMC2715622          DOI： 10.1128/AAC.00004-09

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  18 in total

1.  Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance.

Authors:  D A Fidock; T Nomura; A K Talley; R A Cooper; S M Dzekunov; M T Ferdig; L M Ursos; A B Sidhu; B Naudé; K W Deitsch; X Z Su; J C Wootton; P D Roepe; T E Wellems
Journal:  Mol Cell       Date:  2000-10       Impact factor: 17.970

2.  Plasmodium falciparum var genes are regulated by two regions with separate promoters, one upstream of the coding region and a second within the intron.

Authors:  Michael S Calderwood; Laila Gannoun-Zaki; Thomas E Wellems; Kirk W Deitsch
Journal:  J Biol Chem       Date:  2003-06-27       Impact factor: 5.157

3.  Mapping of the Plasmodium falciparum multidrug resistance gene 5'-upstream region, and evidence of induction of transcript levels by antimalarial drugs in chloroquine sensitive parasites.

Authors:  Alissa Myrick; Anusha Munasinghe; Swati Patankar; Dyann F Wirth
Journal:  Mol Microbiol       Date:  2003-08       Impact factor: 3.501

Review 4.  Chloroquine resistance in Plasmodium vivax.

Authors:  J Kevin Baird
Journal:  Antimicrob Agents Chemother       Date:  2004-11       Impact factor: 5.191

Review 5.  Diagnosis of resistance to chloroquine by Plasmodium vivax: timing of recurrence and whole blood chloroquine levels.

Authors:  J K Baird; B Leksana; S Masbar; D J Fryauff; M A Sutanihardja; F S Wignall; S L Hoffman
Journal:  Am J Trop Med Hyg       Date:  1997-06       Impact factor: 2.345

6.  Identification of the Plasmodium vivax mdr-like gene (pvmdr1) and analysis of single-nucleotide polymorphisms among isolates from different areas of endemicity.

Authors:  Sara Brega; Benoit Meslin; Frédérique de Monbrison; Carlo Severini; Luigi Gradoni; Rachanee Udomsangpetch; Inge Sutanto; François Peyron; Stéphane Picot
Journal:  J Infect Dis       Date:  2004-12-09       Impact factor: 5.226

7.  Evidence for different mechanisms of chloroquine resistance in 2 Plasmodium species that cause human malaria.

Authors:  T Nomura; J M Carlton; J K Baird; H A del Portillo; D J Fryauff; D Rathore; D A Fidock; X Su ; W E Collins; T F McCutchan; J C Wootton; T E Wellems
Journal:  J Infect Dis       Date:  2001-04-27       Impact factor: 5.226

8.  Analysis of the genetic diversity of the Plasmodium falciparum multidrug resistance gene 5' upstream region.

Authors:  Alissa Myrick; Ousmane Sarr; Therese Dieng; Omar Ndir; Souleymane Mboup; Dyann F Wirth
Journal:  Am J Trop Med Hyg       Date:  2005-02       Impact factor: 2.345

9.  Multiple transporters associated with malaria parasite responses to chloroquine and quinine.

Authors:  Jianbing Mu; Michael T Ferdig; Xiaorong Feng; Deirdre A Joy; Junhui Duan; Tetsuya Furuya; G Subramanian; L Aravind; Roland A Cooper; John C Wootton; Momiao Xiong; Xin-zhuan Su
Journal:  Mol Microbiol       Date:  2003-08       Impact factor: 3.501

10.  Increased expression levels of the pvcrt-o and pvmdr1 genes in a patient with severe Plasmodium vivax malaria.

Authors:  Carmen Fernández-Becerra; Maria Jesús Pinazo; Ana González; Pedro L Alonso; Hernando A del Portillo; Joaquim Gascón
Journal:  Malar J       Date:  2009-04-02       Impact factor: 2.979
View more
  37 in total

1.  Degrees of chloroquine resistance in Plasmodium - is the redox system involved?

Authors:  Adele M Lehane; Christopher A McDevitt; Kiaran Kirk; David A Fidock
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2012-12-01       Impact factor: 4.077

2.  Whole-genome sequencing and microarray analysis of ex vivo Plasmodium vivax reveal selective pressure on putative drug resistance genes.

Authors:  Neekesh V Dharia; A Taylor Bright; Scott J Westenberger; S Whitney Barnes; Serge Batalov; Kelli Kuhen; Rachel Borboa; Glenn C Federe; Colleen M McClean; Joseph M Vinetz; Victor Neyra; Alejandro Llanos-Cuentas; John W Barnwell; John R Walker; Elizabeth A Winzeler
Journal:  Proc Natl Acad Sci U S A       Date:  2010-10-29       Impact factor: 11.205

3.  Malaria in selected non-Amazonian countries of Latin America.

Authors:  Myriam Arevalo-Herrera; Martha Lucia Quiñones; Carlos Guerra; Nora Céspedes; Sandra Giron; Martha Ahumada; Juan Gabriel Piñeros; Norma Padilla; Zilka Terrientes; Angel Rosas; Julio Cesar Padilla; Ananias A Escalante; John C Beier; Socrates Herrera
Journal:  Acta Trop       Date:  2011-07-01       Impact factor: 3.112

Review 4.  Advances in genetics and genomics: use and limitations in achieving malaria elimination goals.

Authors:  Sharmini Gunawardena; Nadira D Karunaweera
Journal:  Pathog Glob Health       Date:  2015-05       Impact factor: 2.894

Review 5.  Malaria drug resistance: new observations and developments.

Authors:  Juliana M Sá; Jason L Chong; Thomas E Wellems
Journal:  Essays Biochem       Date:  2011       Impact factor: 8.000

6.  Single-nucleotide polymorphism, linkage disequilibrium and geographic structure in the malaria parasite Plasmodium vivax: prospects for genome-wide association studies.

Authors:  Pamela Orjuela-Sánchez; Nadira D Karunaweera; Mônica da Silva-Nunes; Natal S da Silva; Kézia K G Scopel; Raquel M Gonçalves; Chanaki Amaratunga; Juliana M Sá; Duong Socheat; Rick M Fairhust; Sharmini Gunawardena; Thuraisamy Thavakodirasah; Gawrie L N Galapaththy; Rabindra Abeysinghe; Fumihiko Kawamoto; Dyann F Wirth; Marcelo U Ferreira
Journal:  BMC Genet       Date:  2010-07-13       Impact factor: 2.797

7.  Plasmodium vivax chloroquine resistance and anemia in the western Brazilian Amazon.

Authors:  Marly M Marques; Monica R F Costa; Franklin S Santana Filho; José L F Vieira; Margareth T S Nascimento; Larissa W Brasil; Fátima Nogueira; Henrique Silveira; Roberto C Reyes-Lecca; Wuelton M Monteiro; Marcus V G Lacerda; Maria G C Alecrim
Journal:  Antimicrob Agents Chemother       Date:  2013-10-28       Impact factor: 5.191

8.  Single-nucleotide polymorphism and copy number variation of the multidrug resistance-1 locus of Plasmodium vivax: local and global patterns.

Authors:  Rosa del Carmen Miluska Vargas-Rodríguez; Melissa da Silva Bastos; Maria José Menezes; Pamela Orjuela-Sánchez; Marcelo U Ferreira
Journal:  Am J Trop Med Hyg       Date:  2012-09-04       Impact factor: 2.345

9.  Drug resistance associated genetic polymorphisms in Plasmodium falciparum and Plasmodium vivax collected in Honduras, Central America.

Authors:  Irina T Jovel; Rosa E Mejía; Engels Banegas; Rita Piedade; Jackeline Alger; Gustavo Fontecha; Pedro E Ferreira; Maria I Veiga; Irma G Enamorado; Anders Bjorkman; Johan Ursing
Journal:  Malar J       Date:  2011-12-19       Impact factor: 2.979

Review 10.  Understanding the clinical spectrum of complicated Plasmodium vivax malaria: a systematic review on the contributions of the Brazilian literature.

Authors:  Marcus V G Lacerda; Maria P G Mourão; Márcia A A Alexandre; André M Siqueira; Belisa M L Magalhães; Flor E Martinez-Espinosa; Franklin S Santana Filho; Patrícia Brasil; Ana M R S Ventura; Mauro S Tada; Vanja S C D Couto; Antônio R Silva; Rita S U Silva; Maria G C Alecrim
Journal:  Malar J       Date:  2012-01-09       Impact factor: 2.979
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.