Literature DB >> 19450959

Mechanisms of miRNA-mediated post-transcriptional regulation in animal cells.

Marina Chekulaeva1, Witold Filipowicz.   

Abstract

MicroRNAs (miRNAs) are 20-nt-long to 24-nt-long noncoding RNAs acting as post-transcriptional regulators of gene expression in animals and plants. In mammals, more than 50% of mRNAs are predicted to be the subject of miRNA-mediated control but mechanistic aspects of the regulation are not fully understood and different studies have produced often-contradictory results. miRNAs can affect both the translation and stability of mRNAs. In this report, we review current progress in understanding how miRNAs execute these effects in animals and we discuss some of the controversies regarding different modes of miRNA function.

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Year:  2009        PMID: 19450959     DOI: 10.1016/j.ceb.2009.04.009

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN: 0955-0674            Impact factor:   8.382


  302 in total

Review 1.  Post-transcriptional regulation in metabolic diseases.

Authors:  Wook Kim; Eun Kyung Lee
Journal:  RNA Biol       Date:  2012-06-01       Impact factor: 4.652

2.  PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity.

Authors:  Je-Hyun Yoon; Supriyo De; Subramanya Srikantan; Kotb Abdelmohsen; Ioannis Grammatikakis; Jiyoung Kim; Kyoung Mi Kim; Ji Heon Noh; Elizabeth J F White; Jennifer L Martindale; Xiaoling Yang; Min-Ju Kang; William H Wood; Nicole Noren Hooten; Michele K Evans; Kevin G Becker; Vidisha Tripathi; Kannanganattu V Prasanth; Gerald M Wilson; Thomas Tuschl; Nicholas T Ingolia; Markus Hafner; Myriam Gorospe
Journal:  Nat Commun       Date:  2014-11-04       Impact factor: 14.919

3.  Performing custom microRNA microarray experiments.

Authors:  Xiaoxiao Zhang; Yan Zeng
Journal:  J Vis Exp       Date:  2011-10-28       Impact factor: 1.355

4.  microRNA-34c is a novel target to treat dementias.

Authors:  Athanasios Zovoilis; Hope Y Agbemenyah; Roberto C Agis-Balboa; Roman M Stilling; Dieter Edbauer; Pooja Rao; Laurent Farinelli; Ivana Delalle; Andrea Schmitt; Peter Falkai; Sanaz Bahari-Javan; Susanne Burkhardt; Farahnaz Sananbenesi; Andre Fischer
Journal:  EMBO J       Date:  2011-09-23       Impact factor: 11.598

5.  Characterization of grapevine microR164 and its target genes.

Authors:  Xin Sun; Nicholas Kibet Korir; Jian Han; Ling-Fei Shangguan; Emrul Kayesh; Xiang-Peng Leng; Jing-Gui Fang
Journal:  Mol Biol Rep       Date:  2012-06-24       Impact factor: 2.316

Review 6.  The widespread regulation of microRNA biogenesis, function and decay.

Authors:  Jacek Krol; Inga Loedige; Witold Filipowicz
Journal:  Nat Rev Genet       Date:  2010-07-27       Impact factor: 53.242

Review 7.  The miR-15/107 group of microRNA genes: evolutionary biology, cellular functions, and roles in human diseases.

Authors:  John R Finnerty; Wang-Xia Wang; Sébastien S Hébert; Bernard R Wilfred; Guogen Mao; Peter T Nelson
Journal:  J Mol Biol       Date:  2010-08-01       Impact factor: 5.469

8.  Signatures of RNA binding proteins globally coupled to effective microRNA target sites.

Authors:  Anders Jacobsen; Jiayu Wen; Debora S Marks; Anders Krogh
Journal:  Genome Res       Date:  2010-05-27       Impact factor: 9.043

9.  Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination.

Authors:  Je-Hyun Yoon; Kotb Abdelmohsen; Jiyoung Kim; Xiaoling Yang; Jennifer L Martindale; Kumiko Tominaga-Yamanaka; Elizabeth J White; Arturo V Orjalo; John L Rinn; Stefan G Kreft; Gerald M Wilson; Myriam Gorospe
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

Review 10.  Genome-wide technology for determining RNA stability in mammalian cells: historical perspective and recent advantages based on modified nucleotide labeling.

Authors:  Hidenori Tani; Nobuyoshi Akimitsu
Journal:  RNA Biol       Date:  2012-10-01       Impact factor: 4.652

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