Literature DB >> 19447863

Bringing DNA repair in tumors into focus.

Christopher J Lord1, Alan Ashworth.   

Abstract

Biomarkers are of crucial importance in optimizing cancer therapies. In this edition of Clinical Cancer Research, Bañuelos and colleagues assess H2AX phosphorylation as a predictive biomarker of response to DNA damaging agents. We discuss these results as well as the impact that double strand break repair biomarkers may have in cancer therapy.

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Year:  2009        PMID： 19447863     DOI： 10.1158/1078-0432.CCR-09-0434

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN： 1078-0432            Impact factor:   12.531


  7 in total

Review 1.  Translational research in phase I trials.

Authors:  Angelica Fasolo; Cristiana Sessa
Journal:  Clin Transl Oncol       Date:  2009-09       Impact factor: 3.405

2.  Effects of the novel DNA dependent protein kinase inhibitor, IC486241, on the DNA damage response to doxorubicin and cisplatin in breast cancer cells.

Authors:  David Davidson; Jeremy Grenier; Veronica Martinez-Marignac; Lilian Amrein; May Shawi; Marc Tokars; Raquel Aloyz; Lawrence Panasci
Journal:  Invest New Drugs       Date:  2011-05-13       Impact factor: 3.850

3.  Differential expression of DNA repair genes in Hispanic women with breast cancer.

Authors:  Jaime Matta; Luisa Morales; Julie Dutil; Manuel Bayona; Carolina Alvarez; Erick Suarez
Journal:  Mol Cancer Biol       Date:  2013-02-01

4.  Imaging DNA damage in vivo using gammaH2AX-targeted immunoconjugates.

Authors:  Bart Cornelissen; Veerle Kersemans; Sonali Darbar; James Thompson; Ketan Shah; Kate Sleeth; Mark A Hill; Katherine A Vallis
Journal:  Cancer Res       Date:  2011-05-17       Impact factor: 12.701

5.  Dynamic In Vivo Profiling of DNA Damage and Repair after Radiotherapy Using Canine Patients as a Model.

Authors:  Nadine Schulz; Hassan Chaachouay; Katarzyna J Nytko; Mathias S Weyland; Malgorzata Roos; Rudolf M Füchslin; Franco Guscetti; Stephan Scheidegger; Carla Rohrer Bley
Journal:  Int J Mol Sci       Date:  2017-06-01       Impact factor: 5.923

Review 6.  Genetic characterization of breast cancer and implications for clinical management.

Authors:  Felipe C Geyer; Maria A Lopez-Garcia; Maryou B Lambros; Jorge S Reis-Filho
Journal:  J Cell Mol Med       Date:  2009-09-14       Impact factor: 5.310

7.  A role for eukaryotic initiation factor 4B overexpression in the pathogenesis of diffuse large B-cell lymphoma.

Authors:  E Horvilleur; T Sbarrato; K Hill; R V Spriggs; M Screen; P J Goodrem; K Sawicka; L C Chaplin; C Touriol; G Packham; K N Potter; S Dirnhofer; A Tzankov; M J S Dyer; M Bushell; M MacFarlane; A E Willis
Journal:  Leukemia       Date:  2013-10-18       Impact factor: 11.528
  7 in total

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