Literature DB >> 19447771

Methotrexate, rheumatoid arthritis and infection risk: what is the evidence?

Andrew McLean-Tooke1, Catherine Aldridge, Sheila Waugh, Gavin P Spickett, Lesley Kay.   

Abstract

Low-dose MTX administered weekly remains a mainstay in the therapy of RA. There is a belief amongst rheumatologists that RA patients taking MTX have both an increased risk and severity of infection. Here we review the published data on the risks of infection associated with the use of MTX in patients with RA and make some recommendations for managing MTX in patients with infection.

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Year:  2009        PMID: 19447771     DOI: 10.1093/rheumatology/kep101

Source DB:  PubMed          Journal:  Rheumatology (Oxford)        ISSN: 1462-0324            Impact factor:   7.580


  34 in total

Review 1.  Three decades of low-dose methotrexate in rheumatoid arthritis: can we predict toxicity?

Authors:  Vasco C Romão; Aurea Lima; Miguel Bernardes; Helena Canhão; João Eurico Fonseca
Journal:  Immunol Res       Date:  2014-12       Impact factor: 2.829

2.  [In Process Citation].

Authors:  Christoph Fiehn; Regina Max; Norbert Blank; Andreas Schneider; Reinhard Schneider; Sebastian K G Maier; Jan Becher; Peter Nordbeck; Alexander H Jakob
Journal:  Med Klin (Munich)       Date:  2010-01

Review 3.  Managing the drug treatment of rheumatoid arthritis.

Authors:  Tom D Wilsdon; Catherine L Hill
Journal:  Aust Prescr       Date:  2017-04-03

4.  Acute Hepatitis E Virus infection with coincident reactivation of Epstein-Barr virus infection in an immunosuppressed patient with rheumatoid arthritis: a case report.

Authors:  Detlev Schultze; Bernhard Mani; Günter Dollenmaier; Roland Sahli; Andrea Zbinden; Pierre Alexandre Krayenbühl
Journal:  BMC Infect Dis       Date:  2015-10-29       Impact factor: 3.090

Review 5.  Understanding the Cautions and Contraindications of Immunomodulator and Biologic Therapies for Use in Inflammatory Bowel Disease.

Authors:  H Matthew Cohn; Maneesh Dave; Edward V Loftus
Journal:  Inflamm Bowel Dis       Date:  2017-08       Impact factor: 5.325

6.  Urinary tract infections in patients with rheumatoid arthritis.

Authors:  D Puntis; S Malik; V Saravanan; M Rynne; C Heycock; J Hamilton; C A Kelly
Journal:  Clin Rheumatol       Date:  2012-12-14       Impact factor: 2.980

7.  Methotrexate ameliorates pristane-induced arthritis by decreasing IFN-γ and IL-17A expressions.

Authors:  Wei-kun Hou; Lie-su Meng; Fang Zheng; Yu-rong Wen; Wen-hua Zhu; Cong-shan Jiang; Xiao-jing He; Yan Zhou; She-min Lu
Journal:  J Zhejiang Univ Sci B       Date:  2011-01       Impact factor: 3.066

8.  Tryptophan degradation and neopterin levels in treated rheumatoid arthritis patients.

Authors:  Yesim Ozkan; Guray Mete; Aylin Sepici-Dincel; Vesile Sepici; Bolkan Simsek
Journal:  Clin Rheumatol       Date:  2011-05-10       Impact factor: 2.980

Review 9.  Central Nervous System Infections Associated with Immunosuppressive Therapy for Rheumatic Disease.

Authors:  Michael J Bradshaw; Tracey A Cho; Felicia C Chow
Journal:  Rheum Dis Clin North Am       Date:  2017-08-23       Impact factor: 2.670

10.  [Medicinal prophylaxis during intensified immunosuppression in children and adolescents : part 2].

Authors:  F Speth; N Wellinghausen; J-P Haas
Journal:  Z Rheumatol       Date:  2013-11       Impact factor: 1.372

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